496-93-5
496-93-5 結(jié)構(gòu)式
基本信息
刀豆酸, 大豆氨基酸
O-氨基-L-高絲氨酸
6-硝基-2-氨苯酚-4-磺酸
canaline
L-Canalin
L-CANALINE BASE
O-AMINO-L-HOMOSERINE
L-Canaline L-Canaline
L-Homoserine, O-amino-
L-CANALINE BASE USP/EP/BP
DL-Carnitine DL-Carnitine
2-Amino-4-(aminooxy)butyric acid
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-129476 | 6-硝基-2-氨苯酚-4-磺酸 L-Canaline | 496-93-5 | 1 mg | 1780元 |
| 2026/06/05 | HY-129476 | 6-硝基-2-氨苯酚-4-磺酸 L-Canaline | 496-93-5 | 5 mg | 4590元 |
| 2026/06/05 | HY-129476 | 6-硝基-2-氨苯酚-4-磺酸 L-Canaline | 496-93-5 | 10 mM * 1 mL in Water | 5049元 |
常見問題列表
IC50: 297 nM (
Plasmodium falciparum
);
Ornithine aminotransferase
L-Canaline treatment inhibits the proliferation of PBMCs after stimulation by phorbol 12-myristate-13-acetate (PMA) or via the mixed lymphocyte reaction. The greatest effect is seen with PMA-stimulated cells, where L-canaline has an
IC
50
of 0.26 mM. L-Canaline is slightly less toxic to PBMCs stimulated via the mixed lymphocyte reaction (
IC
50
of 0.54 mM).
L-canaline inhibits L-lysine flux competitively (
K
i
of 4.6 mM) in astrocytes and astrocytoma cells.
L-Canaline decreases the aspartic acid content of tissues of the medulla oblongata of male Wistar rats, but it does not affect the evoked release of this nonprotein amino acid into these tissues.
Intraseptal injection of 100 μg of L-canaline into male Sprague-Dawley rats causes a 90% decrease in the omithine aminotransferase activity of the septum tissues evaluated from animals killed 1 h later.