49642-07-1
49642-07-1 結(jié)構(gòu)式
基本信息
中文別名
化合物 T13011抑胃酶氨酸STATINE
STATINE抑胃酶氨酸
(3S,4S)-(-)-他汀
英文別名
STATINSTATINE
H-STA-OH
S)-Statine
LEU-STATINE
4S)-Statine
(S,S)-Statine
H-STA(3S,4S)-OH
(3S,4S)-STATINE
H-(3S,4S)-STA-OH
物理化學(xué)性質(zhì)
熔點(diǎn)209 °C
比旋光度D15 -20° (c = 0.64 in water)
沸點(diǎn)306.53°C (rough estimate)
密度1.1233 (rough estimate)
折射率1.4476 (estimate)
儲(chǔ)存條件2-8°C
溶解度0.5 M HCl: 50 mg/mL, clear, very faintly yellow
酸度系數(shù)(pKa)3.97±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
Merck13,8879
安全數(shù)據(jù)
常見問(wèn)題列表
生物活性
Statine 是一種罕見的氨基酸，在胃蛋白酶抑制劑的序列中出現(xiàn)兩次, 胃蛋白酶抑制劑是一種對(duì)胃蛋白酶和其他酸性蛋白酶有抑制作用的蛋白酶抑制劑。體外研究
Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. Statine is also an analog of the previously proposed transition state for catalysis by pepsin and other acid proteases.