49642-07-1
49642-07-1 結(jié)構(gòu)式
基本信息
中文別名
化合物 T13011抑胃酶氨酸STATINE
STATINE抑胃酶氨酸
(3S,4S)-(-)-他汀
英文別名
STATINSTATINE
H-STA-OH
S)-Statine
LEU-STATINE
4S)-Statine
(S,S)-Statine
H-STA(3S,4S)-OH
(3S,4S)-STATINE
H-(3S,4S)-STA-OH
物理化學(xué)性質(zhì)
熔點(diǎn)209 °C
比旋光度D15 -20° (c = 0.64 in water)
沸點(diǎn)306.53°C (rough estimate)
密度1.1233 (rough estimate)
折射率1.4476 (estimate)
儲(chǔ)存條件2-8°C
溶解度0.5 M HCl: 50 mg/mL, clear, very faintly yellow
酸度系數(shù)(pKa)3.97±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
Merck13,8879
安全數(shù)據(jù)
常見問題列表
生物活性
Statine 是一種罕見的氨基酸，在胃蛋白酶抑制劑的序列中出現(xiàn)兩次, 胃蛋白酶抑制劑是一種對胃蛋白酶和其他酸性蛋白酶有抑制作用的蛋白酶抑制劑。體外研究
Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. Statine is also an analog of the previously proposed transition state for catalysis by pepsin and other acid proteases.