522-60-1
522-60-1 結(jié)構(gòu)式
基本信息
乙基氫化脫甲奎寧
乙基氫化銅色樹堿
乙基氫化銅色金雞納堿
numoquin
optoquine
Optochine
Numoquine
Ethylhydrocuprein
ETHYLHYDROCUPREINE
hydrocupreineethylether
Hydrocupureine ethyl ether
6’-ethoxy-hydrocinchonidin
物理化學性質(zhì)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-136429 | 乙氫去甲奎寧 Ethylhydrocupreine | 522-60-1 | 25 mg | 780元 |
| 2026/06/05 | HY-136429 | 乙氫去甲奎寧 Ethylhydrocupreine | 522-60-1 | 10 mM * 1 mL in DMSO | 858元 |
| 2026/06/05 | HY-136429 | 乙氫去甲奎寧 Ethylhydrocupreine | 522-60-1 | 50 mg | 1250元 |
常見問題列表
S. pneumoniae
IC50: 25.75 nM (
Plasmodium falciparum
)
ggTas2r1,
ggTas2r2 and ggTas2r7
The mutation rate to Ethylhydrocupreine (Optochin) resistance is estimated using fluctuation analysis in three capsulated S. pneumoniae strains ( S. pneumoniae D39 NCTC 7466, S. pneumoniae R6 ATCC BAA-255 and S. pneumoniae ATCC 49619). The exposure to subinhibitory concentrations of penicillin increased the mutation rate (expressed as mutation per cell division) to Ethylhydrocupreine (Optochin) resistance between 2.1- and 3.1-fold for all three strains studied.
The injection of 1 cc. of a 24 hour dextrose blood broth culture of virulent Type I pneumococci into the right pleural cavity of guinea pigs produces acute suppurative pleuritis on both sides associated with suppurative pericarditis. The injection of 1 cc. of 1:500 solutions of Ethylhydrocupreine hydrochloride into each pleural cavity of guinea pigs at varying intervals up to 24 hours after pleural infection has usually shown a marked curative influence. Similar results are observed with dogs.