53174-06-4
53174-06-4 結(jié)構(gòu)式
基本信息
(S)-(-)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸
Trolox Impurity 2 (Trolox (S)-Isomer)
(S)-(-)-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-C
(2S)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid
(S)-(-)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
(S)-(-)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 98%
(S)-6-Hydroxy-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
(S)-3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
(2S)-2,5,7,8-Tetramethyl-6-hydroxy-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
(2S)-2,5,7,8-Tetramethyl-6-hydroxy-3,4-dihydro-2H-1-benzopyran-2α-carboxylic acid
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
Skin Irrit. 2
STOT SE 3
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-101445B | (S)-(-)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 (S)-Trolox | 53174-06-4 | 50 mg | 500元 |
| 2026/06/05 | HY-101445B | (S)-(-)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 (S)-Trolox | 53174-06-4 | 10 mM * 1 mL in DMSO | 550元 |
| 2026/06/05 | HY-101445B | (S)-(-)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 (S)-Trolox | 53174-06-4 | 100 mg | 850元 |
常見問題列表
The neuroprotective efficacy of antioxidant molecules against iodoacetate (IAA) neurotoxicity in rat cerebellar granule cell (CGC) cultures is investigated. In the absence of MK-801, (S)-Trolox displays marginal neuroprotective effects. In the presence of MK-801 (10 μM), the neuroprotective efficacy of (S)-Trolox is greatly enhanced, giving rise to a recovery in MTT-reductase activity equivalent to 80–100% of control cultures. (S)-Trolox displays EC50 value of 78 μM. The fluorescence increase in IAA-stimulated DCFH-DA-loaded cultures is inhibited in a dose-dependent manner by the antioxidants (S)-Trolox with an IC50 value of 97 μM. The antioxidant (S)-Trolox demonstrate apotent and specific neuroprotective action in an in vitro model of neurodegeneration induced by inhibition of the glycolytic enzyme GAPDH.