579-56-6
中文名稱
鹽酸苯氧丙酚胺
英文名稱
ISOXSUPRINE HYDROCHLORIDE
CAS
579-56-6
EINECS 編號
209-443-6
分子式
C18H24ClNO3
MDL 編號
MFCD00058069
分子量
337.84
MOL 文件
579-56-6.mol
更新日期
2026/07/17 17:10:11
579-56-6 結構式
基本信息
中文別名
鹽酸苯氧丙酚胺異舒普林鹽酸鹽
異克舒令
英文別名
ISOXSUPRINE HCLISOXSUPRINE HYDROCHLORIDE
1-(p-hydroxyphenyl)-2-(1’-methyl-2’-phenoxy)ethylaminopropanol-1hydrochlorid
2-(3-phenoxy-2-propylamino)-1-(p-hydroxyphenyl)-1-propanolhydrochloride
isolait
isoxsuprinhydrochloride
p-hydroxy-alpha-(1-((1-methyl-2-phenoxyethyl)amino)ethyl)-benzylalcohohyd
suprilent
vasodilan
vasoplex
Isoxsuprine
Benzenemethanol, 4-hydroxy-.alpha.-1-(1-methyl-2-phenoxyethyl)aminoethyl-, hydrochloride
1-(p-Hydroxyphenyl)-2-(1'-methyl-2'-phenoxy)ethylaminopropanol-1 hydrochloride
Benzenemethanol, 4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (9CI)
Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI)
Dilavase
Divadilan
Duvadilan
Duviculine
Navilox
所屬類別
分析化學：法醫(yī)和獸醫(yī)標準品物理化學性質
熔點203-204°
儲存條件Inert atmosphere,2-8°C
溶解度Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in methylene chloride.
酸度系數(shù)(pKa)pKa 8.0 (Uncertain);9.8 (Uncertain)
形態(tài)neat
顏色White to off-white
主要應用forensics and toxicology
pharmaceutical (small molecule)
veterinary
pharmaceutical (small molecule)
veterinary
InChI1S/C18H23NO3.ClH/c1-13(12-22-17-6-4-3-5-7-17)19-14(2)18(21)15-8-10-16(20)11-9-15;/h3-11,13-14,18-21H,12H2,1-2H3;1H
InChIKeyQVPSGVSNYPRFAS-UHFFFAOYSA-N
SMILESOC(C(NC(COC1=CC=CC=C1)C)C)C2=CC=C(O)C=C2.Cl
CAS 數(shù)據(jù)庫579-56-6(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞警告
危險性描述H302-H410
危險品標志Xn
危險類別碼R22
安全說明S36
危險品運輸編號UN 3077 9 / PGIII
WGK Germany3
RTECS號DO8225000
海關編碼2922504500
存儲類別11 - Combustible Solids
危險性類別Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Aquatic Acute 1
Aquatic Chronic 1
毒害物質數(shù)據(jù)579-56-6(Hazardous Substances Data)
毒性LD50 in rats (mg/kg): 1750 orally; 164 i.p. (Goldenthal)
鹽酸苯氧丙酚胺價格(試劑級)
| 報價日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
| 2026/07/06 | S5669 | 鹽酸苯氧丙酚胺 Isoxsuprine hydrochloride | 579-56-6 | 25mg | 794.73元 |
| 2026/06/05 | HY-B1270R | 鹽酸苯氧丙酚胺 Isoxsuprine hydrochloride (Standard) | 579-56-6 | 10 mg | 300元 |
| 2026/06/05 | HY-B1270R | 鹽酸苯氧丙酚胺 Isoxsuprine hydrochloride (Standard) | 579-56-6 | 25 mg | 450元 |
常見問題列表
生物活性
Isoxsuprine hydrochloride是β-腎上腺素能受體（beta-adrenergic）激動劑，具有血管擴張活性。靶點
Ki: 13.65 μΜ (myometrial beta-adrenergic receptor), 3.48 μΜ (placcntal beta-adrenergic receptor)
NMDA receptor
體外研究
Results show that Isoxsuprine hydrochloride inhibits circular chemorepellent induced defect (CCID) formation dose dependently (5 to 60?μM) and also inhibits 12(S)-HETE synthesis. Furthermore, Isoxsuprine hydrochloride is the only drug inhibiting the induction of all three mobility markers (MLC2, MYPT and paxillin).
體內研究
Total infarct volume in vehicle-treated animals is 279±25 mm 3 compare to 137±18 mm 3 in Isoxsuprine hydrochloride-treated animals.