600-57-7
600-57-7 結(jié)構(gòu)式
基本信息
11Β-羥孕酮
11Β-羥孕酮(溶液)
11Β-羥孕酮, >98%
11Β-羥基孕-4-烯-3,20-二酮
11Β-羥基-4-孕烯-3,20-二酮
11B-HYDROXYPROGESTERONE
11β-hydroxyprogesterone
HYDROXYPROGESTERONE, 11B-
11BETA-HYDROXYPROGESTERONE
4-PREGNEN-11BETA-3,20-DIONE
4-PREGNEN-11BETA-OL-3,20-DIONE
11beta-Hydroxyprogesterone, >98%
11-beta-hydroxy-pregn-4-ene-20-dione
Progesterone 11beta-Hydroxy Impurity
物理化學(xué)性質(zhì)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-N2337R | 11B-羥孕酮 11beta-Hydroxyprogesterone (Standard) | 600-57-7 | 1 mg | 450元 |
| 2026/06/05 | HY-N2337R | 11B-羥孕酮 11beta-Hydroxyprogesterone (Standard) | 600-57-7 | 5 mg | 900元 |
| 2026/06/05 | HY-N2337R | 11B-羥孕酮 11beta-Hydroxyprogesterone (Standard) | 600-57-7 | 10 mg | 1440元 |
常見問題列表
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Human Endogenous Metabolite
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11OHP displays agonist mineralocorticoid activity. 11β-hydroxyprogesterone activates the transiently expressed hMR in COS-7 cells in a dose-dependent manner with an ED 50 of 10 nM and stimulates Ams/ sc in mpkCCD cl4 cells. Docking 11β-hydroxyprogesterone within the hMR-ligand-binding domain homology model reveals that the agonist activity of 11OHP is caused by contacts between its 11β-hydroxyl group and Asn770.
11β-hydroxyprogesterone causes a significant elevation in blood pressure within 3 days, an effect that persisted throughout the 14-day infusion. 11β-hydroxyprogesterone is potently hypertensinogenic in the rat and that this activity depends on an intact adrenal and at least in part on the activation of mineralocorticoid receptors.