606-59-7
606-59-7 結(jié)構(gòu)式
基本信息
cinnabarinic acid
2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid
3H-Phenoxazine-1,9-dicarboxylic acid, 2-amino-3-oxo-
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-W011417R | 朱砂精酸 Cinnabarinic acid (Standard) | 606-59-7 | 1 mg | 1800元 |
| 2026/06/05 | HY-W011417R | 朱砂精酸 Cinnabarinic acid (Standard) | 606-59-7 | 5 mg | 3600元 |
| 2026/06/05 | HY-W011417R | 朱砂精酸 Cinnabarinic acid (Standard) | 606-59-7 | 10 mg | 5440元 |
常見(jiàn)問(wèn)題列表
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mGluR4
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Cinnabarinic acid (0-100 μM) does not activate mGlu1, mGlu2, mGlu5, mGlu6, mGlu7, and mGlu8 receptors as shown by measurements of [ 3 H]InsP formation. In contrast, cinnabarinic acid acts as a partial agonist of mGlu4 receptors by increasing [ 3 H]InsP formation by approximately 35% at 100 μM, which is 5-fold less efficacious than ACPT-I in activating mGlu4 receptors in HEK293 cells transiently transfected with rat mGlu1, -2, -4, -5, -6, -7, or -8 receptors. Cinnabarinic acid (0-100 μM) reduces cAMP formation in a concentration-dependent manner with an excellent potency and efficacy. At 30 μM, cinnabarinic acid is effective at 30 μM, and substantially inhibits cAMP formation in cultured cerebellar granule cells.