61177-44-4
中文名稱
氟派利多雜質(zhì)
英文名稱
lithium clavulanate
CAS
61177-44-4
分子式
C8H10LiNO5
分子量
207.11
MOL 文件
61177-44-4.mol
61177-44-4 結(jié)構(gòu)式
基本信息
中文別名
克拉維酸鋰 EP標準品 英文別名
purity 96-98%Clavulanate LithiuM
Lithium clavulanoate
Lithium clavulanate CRS
Lithium (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
(2R,3Z,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid lithium salt
(2R,3Z,5β)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid lithium salt
LithiuM (2R-(2alpha,3(Z),5alpha))-3-(2-hydroxyethylidene)-4-oxa-7-oxo-1-azabicyclo(3.2.0)heptane-2-carboxylate
lithium [2R-(2alpha,3(Z),5alpha)]-3-(2-hydroxyethylidene)-4-oxa-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylate
物理化學性質(zhì)
熔點>234°C (dec.)
儲存條件Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度Methanol (Slightly, Heated, Sonicated), Water (Slightly)
形態(tài)neat
顏色Light Beige to Brown
穩(wěn)定性Hygroscopic
主要應(yīng)用pharmaceutical (small molecule)
InChI1S/C8H9NO5.Li/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h1,6-7,10H,2-3H2,(H,12,13);/q;+1/p-1/b4-1-;/t6-,7-;/m1./s1
InChIKeyJMRXTGCDVQLAFM-JSYANWSFSA-M
SMILES[Li+].N21[C@H](O\C(=C/CO)\[C@@H]2C(=O)[O-])CC1=O
克拉維酸鋰價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-A0256B | 克拉維酸鋰 Clavulanate lithium | 61177-44-4 | 1 mg | 230元 |
| 2026/06/05 | HY-A0256B | 克拉維酸鋰 Clavulanate lithium | 61177-44-4 | 5mg | 500元 |
| 2026/06/05 | HY-A0256B | 克拉維酸鋰 Clavulanate lithium | 61177-44-4 | 10mM * 1mLin DMSO | 550元 |
常見問題列表
生物活性
Clavulanate lithium 是一種高效的 β-lactamase 抑制劑，可作為抗生素。靶點
β-lactamase
體外研究
Clavulanate lithium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase.
Clavulanate lithium (0.25, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L.
Cell Viability Assay
| Cell Line: | L. pneumophila NCTC 1119 |
| Concentration: | 0.25 mg/L, 0.5 mg/L, 1 mg/L |
| Incubation Time: | 0-35 hours |
| Result: | Caused a relatively slow inhibition of growth. |