62568-57-4
中文名稱
依米地肽
英文名稱
DSIP
CAS
62568-57-4
分子式
C35H48N10O15
分子量
848.82
MOL 文件
62568-57-4.mol
更新日期
2026/05/29 13:08:18
62568-57-4 結(jié)構(gòu)式
基本信息
中文別名
睡眠肽催睡眠肽
依替多肽
依米地肽
睡眠誘導(dǎo)肽
醋酸依米地肽
DELTA睡眠誘導(dǎo)多肽
依米地肽, ≥97% (HPLC)
DELTA-SLEEP INDUCING肽
DELTA-SLEEP INDUCING PEPTIDE|依米地肽
英文別名
DSIPWAGGDASGE
DSIP 4H2O
EMIDELTIDE
Delta-Sleep
DSIP acetate
Etipolypeptide
DSIP USP/EP/BP
Ftpp/Adipotide
DSIP nonapeptide
所屬類別
生物化工：多肽物理化學(xué)性質(zhì)
沸點(diǎn)1522.7±65.0 °C(Predicted)
密度1.458±0.06 g/cm3(Predicted)
儲(chǔ)存條件−20°C
酸度系數(shù)(pKa)3.18±0.10(Predicted)
形態(tài)粉末
顏色White to off-white
水溶解性Soluble in water at 0.5mg/ml
序列H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
InChIKeyZRZROXNBKJAOKB-GFVHOAGBSA-N
應(yīng)用領(lǐng)域
多肽
依米地肽是由9種氨基酸組成的肽。這類多肽能夠通過(guò)固相合成方法制備出來(lái)。在一些研究中證實(shí)，依米地肽能夠起到改善、誘導(dǎo)睡眠的效果。參考質(zhì)量標(biāo)準(zhǔn)
外觀:白色粉末純度(HPLC) ≥98.0%
醋酸根含量5.0%～12.0%
水分含量≤8.0%
肽含量≥80.0%
常見(jiàn)問(wèn)題列表
用途
依米地肽是一種神經(jīng)肽，具有抗氧化和抗焦慮作用。
體內(nèi)研究
In rabbit infused with δ-Sleep Inducing Peptide (DSIP), the spindle activity is increased, and heart and respiration rate are moderately decreased. δ-Sleep Inducing Peptide (DSIP) may act as a programming modulator at supra-operational level rather than as a transmitter at operational level. δ-Sleep Inducing Peptide (DSIP; 40 μg/kg, i.p.) increases catalase and superoxide dismutase (SOD) activities and malonic dialdehyde (MDA) concentration in the liver homogenate of rats subjected to acute stress, but the opposite effects are observed at 120, and 360 μg/kg.