63-39-8

中文名稱尿苷5'-三磷酸酯

英文名稱 UTP

CAS 63-39-8

EINECS 編號(hào) 243-347-5

分子式 C9H15N2O15P3

MDL 編號(hào) MFCD00274571

分子量 484.14

MOL 文件 63-39-8.mol

更新日期 2026/06/05 14:24:58

63-39-8 結(jié)構(gòu)式

基本信息物理化學(xué)性質(zhì) 安全數(shù)據(jù) 知名試劑公司產(chǎn)品信息尿苷5'-三磷酸酯價(jià)格(試劑級(jí)) 常見問題列表

基本信息

中文別名

尿苷5'-三磷酸酯

英文別名

5'-URIDYLATE TRIPHOSPHATE
URIDINE 5'-TRIPHOSPHATE
URIDINE-5'-TRIPHOSPHATE NA3-SALT
URIDINE-5'-TRIPHOSPHATE SODIUM
URIDINE 5'-TRIPHOSPHATE SODIUM SALT
URIDINE 5-TRIPHOSPHATE TRISODIUM
URIDINE-5'-TRIPHOSPHATE TRISODIUM SALT
URIDINE-5'-TRIPHOSPHORIC ACID, TRISODIUM
UTP
UTP, 3NA
UTP-NA
UTP, NA3H
UTP SODIUM SALT
UTP TRISODIUM SALT
5’-utp
uridine,5’-(tetrahydrogentriphosphate)
uridine5’-triphosphoricacid
uridinetriphosphate
uteplex
Uracylic

所屬類別

醫(yī)藥中間體：雜環(huán)化合物

物理化學(xué)性質(zhì)

密度2.106±0.06 g/cm3(Predicted)

閃點(diǎn)113 °C

儲(chǔ)存條件−20°C

溶解度Easily soluble (water)

酸度系數(shù)(pKa)pK1:7.58 (25°C)

形態(tài)液體

顏色無色

生物來源yeast (Candida Utilis)

水溶解性Water : ≥ 150 mg/mL (309.83 mM)

InChIKeyPGAVKCOVUIYSFO-XVFCMESISA-N

SMILESC(OP(=O)(O)OP(O)(=O)OP(O)(O)=O)[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1O

CAS 數(shù)據(jù)庫63-39-8(CAS DataBase Reference)

EPA化學(xué)物質(zhì)信息Uridine 5'-(tetrahydrogen triphosphate) (63-39-8)

安全數(shù)據(jù)

危險(xiǎn)品標(biāo)志Xn

危險(xiǎn)類別碼R20/21/22-R68/20/21/22

安全說明S22-S26-S36

WGK Germany1

知名試劑公司產(chǎn)品信息

Sigma Aldrich

63-39-8(sigmaaldrich)

尿苷5'-三磷酸酯價(jià)格(試劑級(jí))

報(bào)價(jià)日期	產(chǎn)品編號(hào)	產(chǎn)品名稱	CAS號(hào)	包裝	價(jià)格
2025/05/22	HY-107372	尿苷5'-三磷酸酯 Uridine triphosphate	63-39-8	5 mg	375元
2025/05/22	HY-107372	尿苷5'-三磷酸酯 Uridine triphosphate	63-39-8	10mg	600元
2025/05/22	HY-107372	尿苷5'-三磷酸酯 Uridine triphosphate	63-39-8	50mg	1200元

常見問題列表

生物活性

Uridine triphosphate (UTP;Uridine 5'-triphosphate) 是一種核苷酸，在正常和疾病狀態(tài)時(shí)，調(diào)節(jié)胰腺內(nèi)分泌和外分泌、增殖、通道、轉(zhuǎn)運(yùn)體和細(xì)胞內(nèi)信號(hào)傳導(dǎo)的功能。

靶點(diǎn)

Human Endogenous Metabolite

體外研究

Uridine triphosphate treatment induces Schwannoma cell migration through activation of P2Y2 receptors and through the increase of extracellular matrix metalloproteinase-2 (MMP-2) activation and expression. Uridine triphosphate-induced proliferation is mediated by protein kinase D, Src-family tyrosine kinase, Ca/calmodulin-dependent protein kinase II, phosphatidylinositol 3-kinase (PI3K), Akt, and phospholipase D. Uridine triphosphate increases phosphorylation of Akt through protein kinase C, Src-family tyrosine kinase, Ca/calmodulin-dependent protein kinase II, and PI3K.

體內(nèi)研究

Uridine triphosphate reduces mitochondrial calcium levels following hypoxia. Early or late uridine triphosphate preconditioning is effective to reduce infarct size and superior myocardial function. Uridine triphosphate treatment increases the number of monocytes and macrophages infiltrating the pouch and up-regulates the gene expression of IL-4 and IL-13 in the regional lymph nodes.