636-26-0
中文名稱
4-羥基-2-巰基-5-甲基嘧啶
英文名稱
4-Hydroxy-5-methyl-2-mercaptopyrimidine
CAS
636-26-0
分子式
C5H6N2OS
MDL 編號
MFCD00009777
分子量
142.18
MOL 文件
636-26-0.mol
更新日期
2026/05/15 13:38:35
636-26-0 結(jié)構(gòu)式
基本信息
中文別名
5-甲基-2-硫尿嘧啶4-羥基-2-巰基-5-甲基嘧啶
英文別名
4-HYDROXY-2-MERCAPTO-5-METHYLPYRIMIDINE4-HYDROXY-5-METHYL-2-THIOPYRIMIDINE
5-METHYL-2-THIOURACIL
5-METHYL-2-THIOXO-1,3,5,6-TETRAHYDROPYRIMIDIN-4-ONE
2,3-dihydro-5-methyl-2-thioxo-4(1h)-pyrimidinon
2,3-dihydro-5-methyl-2-thioxo-4(1h)-pyrimidinone
2-thio-thymin
2-Thiothymine
5-Methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
Thiothymine
Thymine, 2-thio-
Uracil, 5-methyl-2-thio-
4-Hydroxy-2-mercapto-5-methylpyrimidine~2-Thiothymine
4(1H)-Pyrimidinone, 2,3-dihydro-5-methyl-2-thioxo- (9CI)
5-METHYL-2-THIOURACIL 98+%
4(1H)-Pyrimidinone, 2,3-dihydro-5-methyl-2-thioxo-
4-Hydroxy-5-methyl-2-mercaptopyrimidine
4-Hydroxy-5-methylpyrimidine-2-thione
5-Methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
1,2-Dihydro-2-thioxo-5-methylpyrimidine-4(3H)-one
所屬類別
醫(yī)藥中間體：甲基嘧啶物理化學性質(zhì)
外觀性狀乙酰乙酸乙酯與硫脲、無水碳酸鈉反應(yīng)得到甲基硫氧嘧啶（收率65.5%），這是一種具有苦杏仁味的結(jié)晶物，用于生產(chǎn)長效冠狀動脈擴張藥潘生丁。
熔點283-286°C
密度1.36
折射率1.6430 (estimate)
儲存條件Sealed in dry,Room Temperature
酸度系數(shù)(pKa)pKa 7.71 (Uncertain)
形態(tài)powder to crystal
顏色White to Almost white
水溶解性509mg/L(25 ºC)
BRN120488
穩(wěn)定性穩(wěn)定但可能對熱或光敏感。與強氧化劑不相容。
InChIInChI=1S/C5H6N2OS/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
InChIKeyZLAQATDNGLKIEV-UHFFFAOYSA-N
SMILESC1(=S)NC=C(C)C(=O)N1
CAS 數(shù)據(jù)庫636-26-0(CAS DataBase Reference)
NIST化學物質(zhì)信息4(1H)-pyrimidinone, 2,3-dihydro-5-methyl-2-thioxo-(636-26-0)
EPA化學物質(zhì)信息5-Methyl-2-thiouracil (636-26-0)
安全數(shù)據(jù)
警示詞警告
危險性描述H315-H319-H335
危險品標志Xi
危險類別碼R22-R40
安全說明S22-S36/37
RTECS號XP2108500
TSCATSCA listed
海關(guān)編碼2933599590