637-60-5
637-60-5 結(jié)構(gòu)式
基本信息
對甲基苯肼鹽酸鹽
對甲苯肼鹽酸鹽
4-METHYLPHENYLHYDRAZINE HYDROCHLORIDE
4-TOLYLHYDRAZINE HCL
4-TOLYLHYDRAZINE HYDROCHLORIDE
P-METHYLPHENYLHYDRAZINE HYDROCHLORIDE
P-TOLYL HYDRAZINE HCL
P-TOLYLHYDRAZINE HYDROCHLORIDE
(4-Methylphenyl)hydrazinemonohydrochloride
(4-methylphenyl)-hydrazinmonohydrochloride
p-tolyl-hydrazinhydrochloride
p-tolylhydrazinium(1+) chloride
P(4)-tolylhydrazine hydrochoride
1-(4-methylphenyl)hydrazine hydrochloride
Tolyl Hydrazine Hcl
p-Tolylhydrazinehydrochloride,98%
-METHYL PHENYL HYDRAZINE HYDROCHLORIDE
4-Methylphenylhydrazine hydrochloride 98%
HYDRAZINE,PARA-TOLYL,HYDROCHLORIDE
PARA-TOLYLHYDRAZINEHCL
p-tolyhydrazine hydrochloride
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
toxic compounds or compounds which causing chronic effects
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Carc. 1B
Skin Sens. 1
制備方法
106-49-0
637-60-5
以4-甲基苯胺為原料合成4-甲基苯肼鹽酸鹽的一般步驟：將4-甲基苯胺（10.7g，0.1mol）與稀鹽酸混合于200ml圓底燒瓶中。緩慢滴加亞硝酸鈉溶液（30ml，7.3g，0.105mol）至上述混合液中。反應(yīng)混合物攪拌1小時后過濾。將濾得的清澈液體滴加到含有亞硫酸鈉（37.8g，0.3mol）的70ml水溶液中，于80℃下反應(yīng)約1.5小時。隨后，緩慢滴加濃鹽酸（25ml，0.3mol），并將反應(yīng)溫度升至95℃，繼續(xù)反應(yīng)約2.5小時。反應(yīng)完成后，將混合物在室溫下靜置過夜，析出4-甲基苯肼鹽酸鹽固體。經(jīng)過濾、干燥后，得到產(chǎn)物12.9g，產(chǎn)率為90.0%。
參考文獻(xiàn)：
[1] Patent: CN108623511, 2018, A. Location in patent: Paragraph 0021
[2] Patent: EP2157088, 2010, A1. Location in patent: Page/Page column 41-42
[3] Russian Chemical Bulletin, 2005, vol. 54, # 10, p. 2417 - 2424
[4] European Journal of Medicinal Chemistry, 2010, vol. 45, # 10, p. 4692 - 4696
[5] European Journal of Medicinal Chemistry, 2011, vol. 46, # 5, p. 1706 - 1712
知名試劑公司產(chǎn)品信息
p-Tolylhydrazine hydrochloride, 98%(637-60-5)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2026/07/06 | A14220 | 對甲苯肼鹽酸鹽, 98% p-Tolylhydrazine hydrochloride, 98% | 637-60-5 | 5g | 230元 |
| 2026/07/06 | 13916 | 對甲苯肼鹽酸鹽 p-Tolylhydrazine hydrochloride, 98%, Thermo Scientific Chemicals | 637-60-5 | 100g | 3938元 |
| 2026/06/06 | T0319 | 對甲苯肼鹽酸鹽 p-Tolylhydrazine Hydrochloride | 637-60-5 | 25G | 130元 |