一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

返回ChemicalBook首頁(yè)>CAS數(shù)據(jù)庫(kù)列表>65195-55-3

65195-55-3

中文名稱 阿維菌素 B1a
英文名稱 Avermectin B1a
CAS 65195-55-3
分子式 C48H72O14
分子量 873.09
MOL 文件 65195-55-3.mol
更新日期 2026/06/01 08:58:31
65195-55-3 結(jié)構(gòu)式 65195-55-3 結(jié)構(gòu)式

基本信息

中文別名
阿巴汀
齊螨素
克螨靈
愛(ài)弗菌素
阿維菌素原料藥
伊維菌素雜質(zhì)3
依維菌素雜質(zhì)1
阿維菌素 B1a
伊維菌素EP雜質(zhì)A
英文別名
C-076B1a
Abamectina
ABERMECTINS
Abamectinum
Avamectin B1a
AbaMectin B1a
avermectin b1a
Antibiotic C-076B1a
Abamectine [french]
Abamectinum [latin]
所屬類別
化學(xué)農(nóng)藥原藥:殺螨劑

物理化學(xué)性質(zhì)

沸點(diǎn)940.9±65.0 °C(Predicted)
密度1.24±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度≥143.4 mg/mL in DMSO; ≥11.86 mg/mL in EtOH with ultrasonic; insoluble in H2O
酸度系數(shù)(pKa)12.42±0.70(Predicted)
形態(tài)粉末
顏色White to light yellow
穩(wěn)定性吸濕性
InChIKeyRRZXIRBKKLTSOM-CGBKEAFXNA-N
EPA化學(xué)物質(zhì)信息Avermectin A1a, 5-O-demethyl-(65195-55-3)

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)健康危害 (GHS08)環(huán)境危害 (GHS09)有毒 (GHS06)
GHS08,GHS09,GHS06
警示詞危險(xiǎn)
危險(xiǎn)性描述H330-H410-H300-H361d-H372
危險(xiǎn)品運(yùn)輸編號(hào)2588
REACH 注冊(cè)登記Active
危險(xiǎn)等級(jí)6.1(a)
包裝類別II
毒性LD20 orl-rat: 10 mg/kg JAFCAU 32,94,84

常見(jiàn)問(wèn)題列表

用途
阿維菌素 B1a是一種大環(huán)內(nèi)酯二糖驅(qū)蟲劑,可與哺乳動(dòng)物 GABAA 受體上的高親和力和低親和力位點(diǎn)結(jié)合。與高親和力位點(diǎn)結(jié)合可激活受體以增加氯離子流入,而與低親和力位點(diǎn)結(jié)合則可阻斷通道。阿維菌素 B1a 可抑制甘氨酸受體拮抗劑士的寧與大鼠脊髓膜和可溶性受體的結(jié)合(Kis 分別為 1.3 和 3.6 μM)。含有阿維菌素 B1a(>80%)和阿維菌素 B1b(~20%,Cay-17453)的配方可用作殺蟲劑和獸醫(yī)驅(qū)蟲配方,如阿維菌素(Cay-19201)。
生物活性
Avermectin B1a 是一種抗寄生蟲劑,能夠使線蟲癱瘓。
體外研究

[ 3 H]AVM B1a preferentially binds to synaptic membranes from several regions of rat brain. [ 3 H]AVM B1a specific binding to intact monolayers of granule cells increases rapidly with time of incubation and reaches equilibrium after approximately 20 min at 24°C. Higher concentrations of [ 3 H]AVM B1a leads to markedly greater nonspecific binding, 60% at 25 nM. Various AVM analogs also produce concentration-dependent inhibition of [ 3 H]AVM B1a binding in intact cerebellar neurons. AVM B1a and moxidectin are similar in potency (IC 50 values, 120 and 126 nM, respectively). AVMB1a-stimulated chloride efflux from mouse brain synaptic vesicles results from the activation of GABA-insensitive chloride channels and that this action is distinct from their previously documented effects on GABA-gated chloride channels in mouse brain preparations.

體內(nèi)研究

Bacteria are significantly inhibited when the AVM B1a concentration is higher than 83.3 mg/kg, while fungi are less impaired in soil. Soil respiration is also inhibited by high concentration AVM B1a, which differs with soil types. The half lethal dosage (LD 50 ) of AVM B1a to soil earthworm is estimated as 4.63 mg × cm 2 in filter paper contact test, and as 24.13 and 17.06 mg/kg, respectively after treated 7 and 14 days in artificial soil. Iin artificial soil, the LC50 of AVM B1a on earthworms are 24.1 mg/kg and 17.1 mg/kg, respectively, for 7 and 14 days. About 80.0% and 94.8% of the accumulated AVM B1a are eliminated respectively in two groups within 1 day after they are exposed to AVM B1a-free soil, but a trace amount of AVM B1a is found for a relative long time in earthworms.

阿維菌素 B1a價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2025/12/22HY-15308阿維菌素 B1a
Avermectin B1a
65195-55-35mg250元
2025/12/22HY-15308阿維菌素 B1a
Avermectin B1a
65195-55-310mM * 1mLin DMSO340元
2025/12/22HY-15308阿維菌素 B1a
Avermectin B1a
65195-55-310mg350元
"65195-55-3" 相關(guān)產(chǎn)品信息
102190-55-6 74567-01-4 123997-64-8 70161-11-4 123997-59-1 71751-41-2 71827-03-7 2999-46-4 14542-93-9 645-96-5 7188-38-7 71831-09-9 113665-89-7 39687-95-1 36635-61-7 2769-64-4 70209-81-3 110415-68-4
望都县| 营口市| 循化| 永泰县| 托克逊县| 灵宝市| 通道| 芒康县| 名山县| 水富县| 牟定县| 罗江县| 葫芦岛市| 鄂尔多斯市| 呼和浩特市| 沛县| 怀来县| 昔阳县| 图木舒克市| 彰武县| 巫溪县| 海宁市| 芷江| 昭平县| 治县。| 黑山县| 贡嘎县| 专栏| 巩义市| 宁乡县| 华蓥市| 崇州市| 武功县| 镇安县| 瓮安县| 八宿县| 奇台县| 黄陵县| 孝昌县| 长宁县| 南平市|