6601-62-3
中文名稱
薊黃素
英文名稱
cirsimaritin
CAS
6601-62-3
分子式
C17H14O6
分子量
314.29
MOL 文件
6601-62-3.mol
更新日期
2026/05/26 09:15:12
6601-62-3 結(jié)構(gòu)式
基本信息
中文別名
薊黃素 英文別名
SkrofuleinScrophulein
6-Methoxygenkwanin
Cirsimaritin >=90% (LC/MS-ELSD)
4',5-Dihydroxy-6,7-dimethoxyflavone
5-Hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-
所屬類別
天然產(chǎn)物：黃酮類化合物物理化學(xué)性質(zhì)
熔點257 °C
沸點563.6±50.0 °C(Predicted)
密度1.402±0.06 g/cm3(Predicted)
儲存條件-20°C
溶解度DMSO: 10 mM
酸度系數(shù)(pKa)6.34±0.40(Predicted)
形態(tài)固體
顏色Light yellow to light brown
主要應(yīng)用metabolomics
vitamins, nutraceuticals, and natural products
vitamins, nutraceuticals, and natural products
InChI1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-3-5-10(18)6-4-9/h3-8,18,20H,1-2H3
InChIKeyZIIAJIWLQUVGHB-UHFFFAOYSA-N
SMILESCOc1cc2OC(=CC(=O)c2c(O)c1OC)c3ccc(O)cc3
LogP1.970 (est)
安全數(shù)據(jù)
常見問題列表
生物活性
Cirsimaritin可以較弱的靶向結(jié)合 GABAA 受體上的苯二氮平位點，并擁有抗抑郁、抗焦慮、抗接種等活性。體內(nèi)研究
Cirsimaritin significantly reduces the anxiety in mice. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg), indicating that the high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds.