677773-32-9
中文名稱
Etamicastat HCl salt
英文名稱
Etamicastat HCl salt
CAS
677773-32-9
分子式
C14H16ClF2N3OS
分子量
347.81
MOL 文件
677773-32-9.mol
更新日期
2026/06/01 16:42:59
677773-32-9 結(jié)構(gòu)式
基本信息
中文別名
依他米司特鹽酸鹽化合物 T11238L
英文別名
Etamicastat HCl saltBIA 5-453 hydrochloride
Etamicastat hydrochloride
應(yīng)用領(lǐng)域
用途一
Etamicastat, also known as BIA 5-453, is a potent, reversible, peripherally selective dopamine β-hydroxylase inhibitor (DBH inhibitor). Chronic dopamine ?-hydroxylase inhibition with etamicastat effectively decreases blood pressure, although does not prevent the development of hypertension in the spontaneously hypertensive rat.