7414-56-4
中文名稱
ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT
英文名稱
ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT
CAS
7414-56-4
分子式
C11H19N5NaO12P3
分子量
529.21
MOL 文件
7414-56-4.mol
7414-56-4 結(jié)構(gòu)式
基本信息
中文別名
AMP-PCP DISODIUMΒ,Γ-亞甲基腺苷 5'-三磷酸 二鈉鹽
Β,Γ-METHYLENEADENOSINE 5′-TRIPHOSPHATE DISODIUM SALT
英文別名
AMP-PCP disodiumAMP-PCP SODIUM SALT
AMP-PCP disodium salt
β,γ-Methyleneadenosine 5′-triphosphate
ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT
Adenylylmethylenediphosphonate disodium salt
B-GAMMA-METHYLENEADENOSINE 5-*TRIPHOSPHA TE SODIUM
β,γ-Methyleneadenosine 5μ-triphosphate disodium salt
BETA,GAMMA-METHYLENEADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
beta,gamma-Methyleneadenosine 5'-triphosphate disodium salt
物理化學(xué)性質(zhì)
儲存條件-20°C
溶解度H2O: 10 mg/mL
形態(tài)solid
顏色white
水溶解性H2O: 10mg/mL
InChIKeyKZCUOVRMGTZINH-LYYWGVPGSA-L
SMILES[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)CP(O)([O-])=O)[C@@H](O)[C@H]3O
安全數(shù)據(jù)
警示詞危險
危險品標(biāo)志T
危險類別碼23/24/25-36/37/38
安全說明22-26-36-45
WGK Germany3
存儲類別6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
toxic compounds or compounds which causing chronic effects
危險性類別Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-106723A | ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT AMP-PCP disodium | 7414-56-4 | 1mg | 600元 |
| 2026/06/05 | HY-106723A | ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT AMP-PCP disodium | 7414-56-4 | 5mg | 1400元 |
| 2026/06/05 | HY-106723A | ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT AMP-PCP disodium | 7414-56-4 | 10mM * 1mLin Water | 1691元 |
常見問題列表
生物活性
AMP-PCP disodium 是一種 ATP 類似物，可以以 Kd 值 為 3.8 μM 來結(jié)合到 Hsp90 的 N 末端結(jié)構(gòu)域。AMP-PCP disodium 結(jié)合有利于 Hsp90 活性同型二聚體的形成。靶點
|
HSP90 3.8 μM (Kd) |
體外研究
AMP-PCP binding favors the formation of the active homodimer of Hsp90 by enhancing the slow-motion featured conformational exchanges of those residues (A117-A141) within the lid segment (A111-G135) and around region. In total, 170 non-proline residues are identified for the triple-labeled Hsp90 bound with AMP-PCP.