76135-31-4

中文名稱 7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽

英文名稱 8-OH-DPAT·hydrobromide

CAS 76135-31-4

分子式 C16H25NO.BrH

分子量 328.29

MOL 文件 76135-31-4.mol

更新日期 2025/05/13 16:21:34

76135-31-4 結(jié)構(gòu)式

基本信息物理化學(xué)性質(zhì) 安全數(shù)據(jù) 圖譜信息 7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽價(jià)格(試劑級(jí)) 常見問題列表

基本信息

中文別名

8-羥基-2-二丙氨基四氫萘溴酸鹽
7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽

英文別名

8-OH-DPAT HRr
Serotonin agonist DPAT
Hydroxy-DPAT hydrobromide, 8-
3-(Dipropylamino)tetralin-5-ol·hydrobrominate
rac-8-Hydroxy-2-dipropylaMinotetralin HydrobroMide
(+/-)-8-Hydroxy(N,N-dipropyl-2-aMino)tetralin HydrobroMide
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide
7-(DipropylaMino)-5,6,7,8-tetrahydro-1-naphthalenol HydrobroMide
1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1)
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide76135-31-4

物理化學(xué)性質(zhì)

熔點(diǎn)221.5-222.0 °C

儲(chǔ)存條件Desiccate at +4°C

溶解度Soluble to 20 mM in water with gentle warming

形態(tài)粉末

顏色White to off-white

EPA化學(xué)物質(zhì)信息1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1) (76135-31-4)

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS) 有害 (GHS07)

GHS07

警示詞警告

危險(xiǎn)性描述H315-H319-H335

防范說明P271-P261

海關(guān)編碼2921199990

圖譜信息

7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽(76135-31-4)核磁圖(¹HNMR)

7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽價(jià)格(試劑級(jí))

報(bào)價(jià)日期	產(chǎn)品編號(hào)	產(chǎn)品名稱	CAS號(hào)	包裝	價(jià)格
2026/06/05	HY-15688	7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽 8-OH-DPAT hydrobromide	76135-31-4	5 mg	500元
2026/06/05	HY-15688	7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽 8-OH-DPAT hydrobromide	76135-31-4	10 mM * 1 mL in DMSO	550元
2026/06/05	HY-15688	7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽 8-OH-DPAT hydrobromide	76135-31-4	10 mg	800元

常見問題列表

生物活性

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) 是一種有效的，選擇性 5-HT1A 激動(dòng)劑，pIC50 為 8.19。8-Hydroxy-DPAT hydrobromide 對(duì) 5-HT1 結(jié)合位點(diǎn)的亞型具有近 1000 倍的選擇性。

靶點(diǎn)

5-HT _1A Receptor

8.19 (pIC ₅₀ )

體外研究

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) has no effect on 5-HT _1B binding at concentrations lower than 100 nM.

體內(nèi)研究

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide; 32, 56, 80, 100 mg/kg; intramuscularly; 15 min prior to the testing session) of the highest dose significantly interferes with sustained attention and reinforcer efficacy (progressive ratio; PR) performance in the 3,4-methylenedioxymethamphetamine (MDMA)-exposed but not control animals.