76135-31-4
中文名稱
7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽
英文名稱
8-OH-DPAT·hydrobromide
CAS
76135-31-4
分子式
C16H25NO.BrH
分子量
328.29
MOL 文件
76135-31-4.mol
更新日期
2025/05/13 16:21:34
76135-31-4 結(jié)構(gòu)式
基本信息
中文別名
8-羥基-2-二丙氨基四氫萘溴酸鹽7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽
英文別名
8-OH-DPAT HRrSerotonin agonist DPAT
Hydroxy-DPAT hydrobromide, 8-
3-(Dipropylamino)tetralin-5-ol·hydrobrominate
rac-8-Hydroxy-2-dipropylaMinotetralin HydrobroMide
(+/-)-8-Hydroxy(N,N-dipropyl-2-aMino)tetralin HydrobroMide
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide
7-(DipropylaMino)-5,6,7,8-tetrahydro-1-naphthalenol HydrobroMide
1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1)
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide76135-31-4
物理化學性質(zhì)
熔點221.5-222.0 °C
儲存條件Desiccate at +4°C
溶解度Soluble to 20 mM in water with gentle warming
形態(tài)粉末
顏色White to off-white
7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-15688 | 7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽 8-OH-DPAT hydrobromide | 76135-31-4 | 5 mg | 500元 |
| 2026/06/05 | HY-15688 | 7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽 8-OH-DPAT hydrobromide | 76135-31-4 | 10 mM * 1 mL in DMSO | 550元 |
| 2026/06/05 | HY-15688 | 7-(二丙基氨基)-5,6,7,8-四氫-1-萘酚氫溴酸鹽 8-OH-DPAT hydrobromide | 76135-31-4 | 10 mg | 800元 |
常見問題列表
生物活性
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) 是一種有效的，選擇性 5-HT1A 激動劑，pIC50 為 8.19。8-Hydroxy-DPAT hydrobromide 對 5-HT1 結(jié)合位點的亞型具有近 1000 倍的選擇性。靶點
|
5-HT 1A Receptor 8.19 (pIC 50 ) |
體外研究
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) has no effect on 5-HT
1B
binding at concentrations lower than 100 nM.
體內(nèi)研究
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide; 32, 56, 80, 100 mg/kg; intramuscularly; 15 min prior to the testing session) of the highest dose significantly interferes with sustained attention and reinforcer efficacy (progressive ratio; PR) performance in the 3,4-methylenedioxymethamphetamine (MDMA)-exposed but not control animals.