78416-81-6
中文名稱
鹽酸曲林菌素
英文名稱
HL 725
CAS
78416-81-6
分子式
C24H28ClN3O3
分子量
441.95
MOL 文件
78416-81-6.mol
更新日期
2023/03/20 15:41:25
78416-81-6 結(jié)構(gòu)式
基本信息
中文別名
曲喹辛鹽酸曲林菌素
英文別名
HL 725HL 725 HCL
TREQUINSIN
Trequinsin, HCl
TREQUINSIN HYDROCHLORIDE
DTCZZBVPTHVXFA-OSMRDGEFSA-N
TREQUINSIN HYDROCHLORIDE MINIMUM 98%
4,6-trimethylphenyl)imino)--2-((monohydrochloride
Trequinsin, Hydrochloride - CAS 78416-81-6 - Calbiochem
4h-pyrimido(6,1-a)isoquinolin-4-one,2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl
物理化學性質(zhì)
熔點210-211 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
儲存條件Desiccate at RT
溶解度DMSO: 100 mM; Ethanol: 100 mM
形態(tài)淡黃色固體
顏色Light yellow to yellow
水溶解性water: 500μM
InChI1S/C24H27N3O3.ClH/c1-14-9-15(2)23(16(3)10-14)25-22-13-19-18-12-21(30-6)20(29-5)11-17(18)7-8-27(19)24(28)26(22)4;/h9-13H,7-8H2,1-6H3;1H/b25-22+;
InChIKeyDTCZZBVPTHVXFA-OSMRDGEFSA-N
SMILESCl[H].COc1cc2CCN3C(=O)N(C)C(\C=C3c2cc1OC)=N\c4c(C)cc(C)cc4C
鹽酸曲林菌素價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-18740A | 鹽酸曲林菌素 Trequinsin hydrochloride | 78416-81-6 | 1 mg | 681元 |
| 2026/06/05 | HY-18740A | 鹽酸曲林菌素 Trequinsin hydrochloride | 78416-81-6 | 5mg | 1500元 |
| 2026/06/05 | HY-18740A | 鹽酸曲林菌素 Trequinsin hydrochloride | 78416-81-6 | 10 mM * 1 mLin DMSO | 1650元 |
常見問題列表
生物活性
Trequinsin hydrochloride (HL 725) 是高效的血小板 CAMP 磷酸二酯酶 (PDE)的抑制劑，IC50的0.25 nM。Trequinsin hydrochloride (HL 725) 是 ADP、膠原蛋白、凝血酶和腎上腺素在體外誘導(dǎo)的血小板聚集的極有效抑制劑。體外研究
Trequinsin hydrochloride exerts besides its cardiovascular and antihypertensive qualities very potent antiplatelet activities.
Trequinsin hydrochloride is an efficacious agonist of [Ca
2+
]
i
.
Cell Viability Assay
| Cell Line: | Samples from healthy volunteer research donors with normal sperm motility parameters in agreement with World Health Organization 2010 criteria. |
| Concentration: | 10 μM. |
| Incubation Time: | 20 min. |
| Result: | Caused a concentrationdependent increase in [Ca 2+ ] i (EC 50 = 6.4 μM [95% confidence interval (CI): 4.1-9.9 μM]). |