847239-17-2
中文名稱
UVI 3003
英文名稱
3-[4-Hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoicacid
CAS
847239-17-2
分子式
C28H36O4
分子量
436.58
MOL 文件
847239-17-2.mol
更新日期
2026/06/04 14:21:33
847239-17-2 結構式
基本信息
中文別名
化合物UVI 30033-[4-羥基-3-[5,6,7,8-四氫-5,5,8,8-四甲基-3-(戊基氧基)-2-萘]苯基]-2-丙酸
英文別名
UVI 3003UVI 3003
UVI-3003
UVI3003
3-[4-Hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoicacid
2-Propenoic acid, 3-[4-hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-
3-[4-Hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoicacid ISO 9001：2015 REACH
所屬類別
催化劑及助劑：紫外線吸收劑物理化學性質
儲存條件Inert atmosphere,Store in freezer, under -20°C
溶解度DMF: 25 mg/ml; DMSO: 15 mg/ml; Ethanol: 20 mg/ml
形態(tài)結晶固體
顏色White to off-white
InChI1S/C28H36O4/c1-6-7-8-15-32-25-18-23-22(27(2,3)13-14-28(23,4)5)17-21(25)20-16-19(9-11-24(20)29)10-12-26(30)31/h9-12,16-18,29H,6-8,13-15H2,1-5H3,(H,30,31)/b12-10+
InChIKeyAPJSHECCIRQQDV-ZRDIBKRKSA-N
SMILESCC(CCC1(C)C)(C)C2=C1C=C(C3=C(O)C=CC(C=CC(O)=O)=C3)C(OCCCCC)=C2
UVI 3003價格(試劑級)
| 報價日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-107500 | UVI 3003 | 847239-17-2 | 1 mg | 545元 |
| 2026/06/05 | HY-107500 | UVI 3003 UVI 3003 | 847239-17-2 | 5mg | 1200元 |
| 2026/06/05 | HY-107500 | UVI 3003 UVI 3003 | 847239-17-2 | 10mM * 1mLin DMSO | 1320元 |
常見問題列表
生物活性
UVI 3003 是一種高度選擇性的 retinoid X receptor (RXR) 抑制劑，在 Cos7 細胞中，抑制非洲爪蟾蜍和人 RXRα 的活性，IC50 值分別為 0.22 和 0.24 μM。靶點
IC50: 0.22 μM (Xenopus RXRα, in Cos7 cells), 0.24 μM (Human RXRα, in Cos7 cells)
體外研究
UVI3003 inhibits the activity of xenopus and human RXRα, with IC 50 s of 0.22 and 0.24 μM, respectively. UVI3003 fully activates xPPARγ with an EC 50 of 12.6 μM, and is almost completely inactive on hPPARγ and mPPARγ. UVI 3003 (10 μM) does not change the proliferation rate of extraocular muscles (EOM)-derived or LEG-derived EECD34 cells. UVI 3003 causes a 65.4% difference in EECD34 cell fusion and desmin expression.