85392-79-6
85392-79-6 結(jié)構(gòu)式
基本信息
中文別名
吲達(dá)尼定 英文別名
IndanidineIndanidinum
Unii-mp564ife34
Indanidine [inn]
4-(2-Imidazolin-2-ylamino)-2-methyl-2H-imidazole
N-(2-Imidazolin-2-yl)-2-methyl-2H-indazol-4-amine
2H-Imidazole, 4-(2-imidazolin-2-ylamino)-2-methyl-
N-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-2H-indazol-4-amine
2H-Indazol-4-amine, N-(4,5-dihydro-1H-imidazol-2-yl)-2-methyl-
物理化學(xué)性質(zhì)
沸點(diǎn)413.3±37.0 °C(Predicted)
密度1.40±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)8.83±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
常見問題列表
生物活性
Indanidine 是一種 α-腎上腺素能激動(dòng)劑。靶點(diǎn)
alpha-adrenergic
體內(nèi)研究
The selective alpha 1-adrenoceptor agonist, Indanidine, also behaved as a partial agonist in the aorta and produced no significant contractions of the small mesenteric artery. Since Idazoxan and Indanidine have been reported to raise blood pressure in the pithed rat via an action at vascular alpha 1-adrenoceptors, these results call into question the reliability of the small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity in vivo.