85392-79-6
85392-79-6 結(jié)構(gòu)式
基本信息
中文別名
吲達尼定 英文別名
IndanidineIndanidinum
Unii-mp564ife34
Indanidine [inn]
4-(2-Imidazolin-2-ylamino)-2-methyl-2H-imidazole
N-(2-Imidazolin-2-yl)-2-methyl-2H-indazol-4-amine
2H-Imidazole, 4-(2-imidazolin-2-ylamino)-2-methyl-
N-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-2H-indazol-4-amine
2H-Indazol-4-amine, N-(4,5-dihydro-1H-imidazol-2-yl)-2-methyl-
物理化學(xué)性質(zhì)
沸點413.3±37.0 °C(Predicted)
密度1.40±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)8.83±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
常見問題列表
生物活性
Indanidine 是一種 α-腎上腺素能激動劑。靶點
alpha-adrenergic
體內(nèi)研究
The selective alpha 1-adrenoceptor agonist, Indanidine, also behaved as a partial agonist in the aorta and produced no significant contractions of the small mesenteric artery. Since Idazoxan and Indanidine have been reported to raise blood pressure in the pithed rat via an action at vascular alpha 1-adrenoceptors, these results call into question the reliability of the small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity in vivo.