862574-87-6
862574-87-6 結(jié)構(gòu)式
基本信息
1-(2,2-二氟-1,3-苯并二噁茂-5-基)環(huán)丙烷甲腈
1-(2,2-二氟苯并[D][1,3]二氧雜環(huán)戊烯-5-基)環(huán)丙基腈
K1194(1-(2,2-二氟苯并[D][1,3]二氧雜環(huán)戊烯-5-基)環(huán)丙基腈)
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile
Cyclopropanecarbonitrile, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-
1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANE-1-CARBONITRILE
1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile
1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonitrile
物理化學(xué)性質(zhì)
制備方法
![2-(2,2-二氟苯并[D][1,3]二氧雜環(huán)戊烯-5-基)乙氰](/CAS/20150408/GIF/68119-31-3.gif)
68119-31-3
107-04-0
862574-87-6
以(2,2-二氟-1,3-苯并二氧雜環(huán)戊烯-5-基)-乙腈（1.0當(dāng)量）為原料，與50wt% KOH水溶液（5.0當(dāng)量）、1-溴-2-氯乙烷（1.5當(dāng)量）及四丁基溴化銨（0.02當(dāng)量）混合，于70℃下加熱反應(yīng)1小時(shí)。反應(yīng)完成后，冷卻反應(yīng)混合物，隨后用甲基叔丁基醚（MTBE）和水進(jìn)行萃取處理。有機(jī)相依次用水和鹽水洗滌，經(jīng)無(wú)水硫酸鈉干燥后，減壓濃縮除去溶劑，得到目標(biāo)產(chǎn)物1-(2,2-二氟-1,3-苯并二氧雜環(huán)戊烯-5-基)環(huán)丙烷甲腈。
參考文獻(xiàn)：
[1] Patent: WO2009/73757, 2009, A1. Location in patent: Page/Page column 21
[2] Patent: WO2010/37066, 2010, A2. Location in patent: Page/Page column 12; 26
[3] Patent: US2016/324788, 2016, A1. Location in patent: Paragraph 0361; 0362
[4] Patent: WO2009/76142, 2009, A2. Location in patent: Page/Page column 51
[5] Patent: US2007/244159, 2007, A1. Location in patent: Page/Page column 79
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/08/19 | XW0286257487603 | 1-(2,2-二氟苯并二氧代-5-基)環(huán)丙烷甲腈 | 862574-87-6 | 10G | 601元 |
| 2024/08/19 | XW0286257487602 | 1-(2,2-二氟苯并二氧代-5-基)環(huán)丙烷甲腈 | 862574-87-6 | 5G | 301元 |
| 2024/08/19 | XW0286257487601 | 1-(2,2-二氟苯并二氧代-5-基)環(huán)丙烷甲腈 | 862574-87-6 | 1G | 61元 |