863329-65-1
中文名稱
(2'R)-2'-脫氧-2'-氟-2'-甲基尿苷 3',5'-二苯甲酸酯
英文名稱
(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate
CAS
863329-65-1
分子式
C24H21FN2O7
分子量
468.43
MOL 文件
863329-65-1.mol
更新日期
2026/05/14 08:26:08
863329-65-1 結(jié)構(gòu)式
基本信息
中文別名
索菲布韋中間體5索福斯布韋雜質(zhì)96
索氟布韋中間體SF-C2
索氟布韋 中間體 SF-2
(2'R)-2'-脫氧-2'-氟-2'-甲基尿苷 3',5'-二苯甲酸酯
英文別名
Sofosbuvir Intermediate 33',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine
3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-2'-C-Methyluridine
(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate
URIDINE, 2'-DEOXY-2'-FLUORO-2'-METHYL-, 3',5'-DIBENZOATE, (2'R)-
2'Deoxy-2'fluoro-2'- Methyl- 3'5'-bis-o- (phenylcarbonyl) uridine
[(2R,3R,4R,5R)-3-Benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-tetrahydrofuran-2-yl
[(2R,3R,4R,5R)-3-Benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl benzoate
((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-fluoro-4-Methyltetrahydrofuran-2-yl)Methyl benzoate
所屬類別
分析化學(xué)：藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品物理化學(xué)性質(zhì)
熔點(diǎn)256-258℃
密度1.42
儲(chǔ)存條件Storage temp. 2-8°C
酸度系數(shù)(pKa)9.39±0.10(Predicted)
外觀White to off-white Solid
水溶解性3.7mg/L
InChIKeyOUDQYAYIRAUNLO-PDKZGUECSA-N
SMILESC(OC(=O)C1=CC=CC=C1)[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@@](F)(C)[C@@H]1OC(=O)C1=CC=CC=C1
