869884-78-6
中文名稱
雷得唑來
英文名稱
Radezolid
CAS
869884-78-6
分子式
C22H23FN6O3
分子量
438.45
MOL 文件
869884-78-6.mol
更新日期
2026/02/24 11:11:13
869884-78-6 結構式
基本信息
中文別名
雷得唑來雷得唑來RADEZOLID
N-[[(5S)-3-[2-氟-4'-[[(1H-1,2,3-三唑-5-基甲基)氨基]甲基][1,1'-聯(lián)苯]-4-基]-2-氧代-5-惡唑啉基]甲基]乙酰胺
英文別名
RX-1741RX 1741
radezolid
Unii-53pc6lo35w
RX-1741
RX 1741
RX1741
N-[[(5S)-3-[2-Fluoro-4'-[[(1H-1,2,3-triazol-5-yLmethyl)amino]methyl][1,1'-biphenyl]-4-yl]-2-ox
(5S)-N-[3-(2-fluoro-4'-{[(1H-[1,2,3]triazol-4-ylmethyl)amino]methyl}biphenyl-4-yl)-2-oxo-oxazolidin-5-ylmethyl]acetamide
N-[[(5S)-3-[2-Fluoro-4'-[[(1H-1,2,3-triazol-5-ylmethyl)amino]methyl][1,1'-biphenyl]-4-yl]-2-oxo-5-oxazolidinyl]methyl]acetamide
Acetamide, N-[[(5S)-3-[2-fluoro-4'-[[(1H-1,2,3-triazol-5-ylmethyl)amino]methyl][1,1'-biphenyl]-4-yl]-2-oxo-5-oxazolidinyl]methyl]-
所屬類別
生物化工：激動劑抑制劑物理化學性質(zhì)
沸點712.5±60.0 °C(Predicted)
密度1.336
儲存條件-20°C儲存
溶解度≥43.8 mg/mL in DMSO; insoluble in H2O; ≥18.08 mg/mL in EtOH with gentle warming
酸度系數(shù)(pKa)15.53±0.46(Predicted)
形態(tài)固體
顏色White to off-white
雷得唑來價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-14800 | 雷得唑來 Radezolid | 869884-78-6 | 1 mg | 600元 |
| 2026/06/05 | HY-14800 | 雷得唑來 Radezolid | 869884-78-6 | 5mg | 997元 |
| 2026/06/05 | HY-14800 | 雷得唑來 Radezolid | 869884-78-6 | 10mM * 1mLin DMSO | 1096元 |
常見問題列表
生物活性
Radezolid (RX-1741) 是一種噁唑烷酮類抗生素。Radezolid 對葡萄球菌，衣原體和軍團菌具有活性，對 Linezolid 耐藥菌株也具有活性。體外研究
Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid shows a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants.