875-35-4
875-35-4 結(jié)構(gòu)式
基本信息
3-氰基-4-甲基-2,6-二氯吡啶
2,6-二氯-4-甲基-3-吡啶氰
2.6-二氯-3-氰基-4-甲基吡啶
2,6-二氯-4-甲基尼克腈
2.6-二氯-3-氰基-4-甲基吡啶,3-氰基-4-甲基-2,6-二氯吡啶
2,6-二氯-3-腈基-4-甲基 吡啶
2,6-DICHLORO-4-METHYL-3-CYANOPYRIDINE
2,6-DICHLORO-4-METHYLNICOTINONITRILE
2,6-DICHLORO-4-METHYLPYRIDINE-3-CARBONITRILE
3-CYANO-2,6-DICHLORO-4-METHYLPYRIDINE
3-Cyano-4-methyl-2,6-dichloropyridine
3-PYRIDINECARBONITRILE, 2,6-DICHLORO-4-METHYL-
BUTTPARK 43\57-14
IFLAB-BB F0907-8363
3-Cyano-2,6-Dichloro-4-Methylpyridine 2,6-Dichloro-3-Cyano-4-Methylpyridine
3-Cyano-2,6-dichloro-4-methyl
2,6-DICHLORO-4-METHYL-3-PYRIDINECARBONITRILE
3-Cyano-2,6-dichloro-GAMMA-picoline
2,6-DICHLORO-4-METHYLNICOTINONITRILE (3-CYANO-2,6-DICHLORO-4-METHYLPYRIDINE)
3-Cyano-2,6-Chloro-4-methylpyridine
2,6-Dichloro-4-methylnicotinonitrile ,99%
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
toxic compounds or compounds which causing chronic effects
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Eye Dam. 1
Skin Irrit. 2
Skin Sens. 1
STOT SE 3
制備方法
5444-02-0
875-35-4
以6-羥基-4-甲基-2-氧代-1,2-二氫吡啶-3-甲腈為原料合成3-氰基-4-甲基-2,6-二氯吡啶的一般步驟：將6-羥基-4-甲基-2-氧代-1,2-二氫吡啶-3-甲腈（28.0 g，195.2 mmol）溶于三氯氧磷（60.0 mL）中。將反應(yīng)混合物轉(zhuǎn)移至壓力管中，密封后加熱至180℃，反應(yīng)6小時(shí)。反應(yīng)完成后，冷卻至室溫，減壓蒸餾除去過(guò)量的三氯氧磷。緩慢向殘余物中加入碎冰，析出固體。過(guò)濾收集固體，真空干燥，得到目標(biāo)產(chǎn)物3-氰基-4-甲基-2,6-二氯吡啶，產(chǎn)率為92%，無(wú)需進(jìn)一步純化。
參考文獻(xiàn)：
[1] Journal of Heterocyclic Chemistry, 1995, vol. 32, # 3, p. 979 - 984
[2] Patent: WO2014/165232, 2014, A1. Location in patent: Paragraph 0174; 0175
[3] Patent: US2015/119387, 2015, A1. Location in patent: Paragraph 0175; 0176
[4] Patent: JP2017/95498, 2017, A. Location in patent: Paragraph 0079; 0080
[5] Patent: CN104530042, 2017, B. Location in patent: Paragraph 0171; 0177; 0178; 0179
知名試劑公司產(chǎn)品信息
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/12/22 | XW08753543 | 2,6-二氯-3-氰基-4-甲基吡啶 2,6-dichloro-4-methylnicotinonitrile;3-cyano-4-methyl-2,6-dichloropyridine | 875-35-4 | 25G | 38元 |
| 2025/12/22 | D3346 | 2,6-二氯-3-氰基-4-甲基吡啶 2,6-Dichloro-3-cyano-4-methylpyridine | 875-35-4 | 5G | 80元 |
| 2025/12/22 | XW08753542 | 2,6-二氯-3-氰基-4-甲基吡啶 2,6-dichloro-4-methylnicotinonitrile;3-cyano-4-methyl-2,6-dichloropyridine | 875-35-4 | 5G | 27元 |