93285-75-7
中文名稱(chēng)
N-碘代乙?；?N'-生物素基-1,6-己二胺
英文名稱(chēng)
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
CAS
93285-75-7
分子式
C18H31IN4O3S
分子量
510.43
MOL 文件
93285-75-7.mol
更新日期
2026/07/14 17:33:00
93285-75-7 結(jié)構(gòu)式
基本信息
中文別名
凱新生物碘代乙?；鵏C生物素
N-碘代乙酸基-N-生物素己二胺
N-碘代乙?；?N'-生物素基-1,6-己二胺
英文別名
IODOACETYL LC BIOTINN-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE
N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE
N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine
N-BIOTINYL-N'-(IODOACETYL)-1,6-HEXANEDIAMINE
N-Biotinyl-Na€-(iodoacetyl)-1,6-hexanediamine
N-Iodoacetyl-N-biotinylhexylenediaMine(Iodoacetyl-LC-Biotin)
(3aS,4S,6aR)-Hexahydro-N-[6-[(iodoacetyl)amino]hexyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
(3aS,4S,6aR)-Hexahydro-N-[6-[(2-iodoacetyl)aMino]hexyl]-2-oxo-1H-thieno[3,4-d]iMidazole-4-pentanaMide
1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[6-[(iodoacetyl)aMino]hexyl]-2-oxo-, (3aS,4S,6aR)-
物理化學(xué)性質(zhì)
沸點(diǎn)793.7±60.0 °C(Predicted)
密度1.414±0.06 g/cm3 (20 ºC 760 Torr)
儲(chǔ)存條件Sealed in dry,2-8°C
溶解度≥51 mg/mL in DMSO with gentle warming; insoluble in EtOH; insoluble in H2O
酸度系數(shù)(pKa)13.90±0.40(Predicted)
形態(tài)固體
顏色White to off-white
安全數(shù)據(jù)
常見(jiàn)問(wèn)題列表
生物活性
Iodoacetyl-LC-biotin 是一種生物素化的親電子探針，可用于研究蛋白質(zhì)共價(jià)結(jié)合至亞細(xì)胞蛋白質(zhì)組的范圍和特征。體外研究
Iodoacetyl-LC-biotin (IAB) (50-200 μM; 6-24 h) increases LDH leakage in HEK293 cells in a time- and dose-dependant manner.
IAB (50-200 μM; 24 h) causes the release of cytochrome c from the mitochondria to the cytosol in HEK293 cells.