93363-11-2
中文名稱
3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide
英文名稱
3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide
CAS
93363-11-2
分子式
C12H11N3OS
分子量
245.3
MOL 文件
93363-11-2.mol
更新日期
2023/03/17 20:03:08
93363-11-2 結(jié)構(gòu)式
基本信息
中文別名
化合物 T10159化合物48740 RP
英文別名
48740RpRp 55779
48740 Rp
RP-48740
3-(3-Pyridinyl)-1H-pyrrolo[1,2-c]thiazole-7-carboxamide
3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide
1H,3H-Pyrrolo(1,2-C)thiazole-7-carboxamide, 3-(3-pyridinyl)-
物理化學性質(zhì)
沸點516.4±50.0 °C(Predicted)
密度1.49±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)16.43±0.40(Predicted)
3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-100153 | 48740 RP | 93363-11-2 | 1 mg | 7200元 |
常見問題列表
生物活性
48740 RP (RP-55778) 是一種血小板激活因子 (PAF) 拮抗劑。靶點
PAF
體內(nèi)研究
48740 RP (RP-55778) is a platelet-activating factor (PAF) antagonist. In animals treated with 48740 RP only, the number of platelets is increased at a time corresponding to 2 and 4 h after the exposure to lipopolysaccharide (LPS) and the number of eosinophils is also slightly increased. Treatment with 48740 RP in combination with the LPS exposure does not influence the increase in neutrophils seen 2 and 4 h after exposure. At 24 h the increase in the number of neutrophils is about half that in control animals. No effects are found on the LPS-induced increase in number of platelets. In animals pretreated with 48740 RP, there is a significant reduction in capillary permeability.