95232-68-1
95232-68-1 結構式
基本信息
中文別名
替諾柳 英文別名
Tenosal2-(2-thiophenecarboxy)benzoic acid
2-(thiophene-2-carbonyloxy)benzoic acid
2-Thiophenecarboxylic acid, 2-carboxyphenyl ester
常見問題列表
生物活性
Tenosal 是一種通過將水楊酸與 2-噻吩羧酸酯化而得到的新型化合物，具有抗炎，鎮(zhèn)痛和退熱特性。體內(nèi)研究
Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties. Extraction recovery measured is on average 95.75% for Tenosal, 98.71% for salicylic acid (SA) and 91.11% for TA. In the whole analysis of Tenosal extracted from plasma, the inter-assay coefficient of variation (C.V.) ranges from 1.00 to 5.86% and the intra assay C.V. is 5.01%. The administration of Tenosal allows a higher bioavailability of SA to be achieved than after dosing with ASA.