伊曲茶堿雜質(zhì)
|
|
|
- CAS號:
- 160434-48-0
- 英文名:
- 4-DesMethyl Istradefylline
- 英文別名:
- Itraphylline impurities6;4-Desmethyl Istradefylline;Istradefylline Impurity 14;Itraphylline impurities869;Istradefylline M1 metabolite;4-DesMethyl Istradefylline impurity;Istradefylline 4-O-Desmethyl Impurity;(E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione;(E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-3,7-dihydro-1H-purine-2,6-dione;1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI)
- 中文名:
- 伊曲茶堿雜質(zhì)
- 中文別名:
- 伊曲茶堿10;伊曲茶堿雜質(zhì)14;4-去甲基異氟烷;伊曲茶堿雜質(zhì)869;4-去甲基伊曲茶堿;化合物 4-Desmethyl Istradefylline
- CBNumber:
- CB12695351
- 分子式:
- C19H22N4O4
- 分子量:
- 370.4
- MOL File:
- 160434-48-0.mol
|
|
|
伊曲茶堿雜質(zhì)化學(xué)性質(zhì)
-
沸點(diǎn):
-
604.8±65.0 °C(Predicted)
-
|
-
密度:
-
1.30±0.1 g/cm3(Predicted)
-
|
-
酸度系數(shù)(pKa):
-
9.88±0.31(Predicted)
-
|
伊曲茶堿雜質(zhì)性質(zhì)、用途與生產(chǎn)工藝
4-Desmethyl Istradefylline 是 Istradefylline 的代謝物。Istradefylline 是一種有效的，選擇性的，可口服的 adenosine A2A receptor 拮抗劑，在帕金森疾病模型試驗中，Ki 值為 2.2 nM。
用途
4-Desmethyl Istradefylline is an impurity of Istradefylline (I927000), a selective A(2A) antagonist used in the treatment of Parkinson鈥檚 disease. 4-Desmethyl Istradefylline have also been shown to exh
ibit inhibitory potency towards adenosine A2A receptors and is classified as its an adenosine A2A receptor antagonist.
伊曲茶堿雜質(zhì)
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
160434-48-0, 伊曲茶堿雜質(zhì) 相關(guān)搜索:
伊曲茶堿雜質(zhì) 1,3-二乙基-5-亞硝基-6-氨基脲嘧啶 6-氨基-1,3-二乙基-2,4(1H,3H)-嘧啶二酮 咖啡酸 IstradefyllineDimer2 伊曲茶堿雜質(zhì)10 4-氨基-2,6-二羥基嘧啶 3,4-二甲氧基肉桂酸 伊曲茶堿雜質(zhì)7 伊曲茶堿雜質(zhì) 伊曲茶堿雜質(zhì) 伊曲茶堿雜質(zhì) 伊曲茶堿雜質(zhì)2 伊曲茶堿 伊曲茶堿雜質(zhì)8 (E)-1,3-二乙基-6-氨基-5-(3,4-二甲氧基苯丙烯?；?氨基尿嘧啶 5,6-二氨基-1,3-二乙基尿嘧啶鹽酸鹽
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
- 抑制劑
- 雜質(zhì)對照品
- 化合物 4-Desmethyl Istradefylline
- 伊曲茶堿10
- 伊曲茶堿雜質(zhì)869
- 4-去甲基異氟烷
- 4-去甲基伊曲茶堿
- 伊曲茶堿雜質(zhì)14
- 160434-48-0
- (E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-3,7-dihydro-1H-purine-2,6-dione
- 4-Desmethyl Istradefylline
- Itraphylline impurities6
- Itraphylline impurities869
- Istradefylline M1 metabolite
- Istradefylline 4-O-Desmethyl Impurity
- 1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI)
- Istradefylline Impurity 14
- 4-DesMethyl Istradefylline impurity
- (E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione