(R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚
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- CAS號:
- 30199-26-9
- 英文名:
- XANTHORRHIZOL
- 英文別名:
- XANTHORRHIZOL;(R)-Xanthorrizol;Einecs 250-090-2;(-)-Xanthorrizol;XANTHORRHIZOL(RG);(R)-(-)-Xanthorrhizol;Xanthorrhizol, Antioxidant agent;(R)-5-(1,5-dimethyl-4-hexenyl)-o-cresol;5-(1,5-Dimethyl-4-hexenyl)-2-methylphenol;Xanthorrhizol from Cucuma xanthorrhiza
- 中文名:
- (R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚
- 中文別名:
- 黃藥醇;黃藥唑;黃根醇;束骨姜黃醇;(R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚;XANTHORRHIZOL,ANTIOXIDANT AGENT
- CBNumber:
- CB4202828
- 分子式:
- C15H22O
- 分子量:
- 218.33
- MOL File:
- 30199-26-9.mol
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(R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚化學(xué)性質(zhì)
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沸點:
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326.9±11.0 °C(Predicted)
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密度:
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0.948±0.06 g/cm3(Predicted)
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儲存條件:
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−20°C
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溶解度:
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Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
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酸度系數(shù)(pKa):
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10.34±0.10(Predicted)
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形態(tài):
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Colorless to light yellow oil.
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顏色:
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Pale Yellow to Light Yellow
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化妝品成分功效:
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ANTI-SEBUM
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LogP:
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5.480
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(R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚性質(zhì)、用途與生產(chǎn)工藝
Xanthorrhizol 是從 Curcuma xanthorrhiza 中分離出來的，一種有效的抗菌劑。
Xanthorrhizol is a potential antibacterial agent from
Curcuma xanthorrhiza
against
streptocpccus
mutants. SEM analysis shows that, treatment of Candida species with MIC of Xanthorrhizol affects the external morphology of these yeasts. Cells incubated in the presence of Xanthorrhizol demonstrate a greater tendency to clump compared with the control cultures. Xanthorrhizol treated
C. glabrata
cells shows minor abnormalities without a smooth or a slightly awkward surface. Xanthorrhizol-treated Candida cells exhibit deformation and protrusions on the cell surface, which is more clearly demonstrated with
C. guilliermondii
and
C. parapsilosis
. In general, Candida exposed to, Xanthorrhizol at concentrations 1 x MICs exhibits substantial ultrastructural abnormalities such as shape deformation, protrusion, rugged cells surface, and clumping.
Ear edema induced by the topical application of TPA is suppressed by pre-treatment with Xanthorrhizol in a doserelated manner (P<0.005). Topical application of Xanthorrhizol alone does not induce ear edema in mice. All the mice treated with 7.5 nM TPA for 19 weeks after initiation by DMBA developed an average of 15.5±2.3 skin tumors per mouse (tumor multiplicity). Pre-treatment with 2 and 6 μM Xanthorrhizol reduces tumor multiplicity to 6.9±1.1 (P<0.005) and 4.0±1.1 (P<0.005), respectively, at 19 weeks. In addition, Xanthorrhizol at 2 and 6 μM dose dependently lowers the percentage of tumor-bearing mice (tumor incidence) to 80 and 57%, respectively, at the termination of the experiments. Furthermore, the tumor multiplicity (P<0.05) and incidence are reduced in the DMBA-initiated mice that are topically treated with Xanthorrhizol for 6 weeks after the induction of papillomas with hyperplasia, mild dysplasia and moderate dysplasia by topical TPA application for 6, 18 and 24 weeks, respectively. The increased ODC expression in mouse epidermis with acute inflammation and tumor promotion induced by TPA is inhibited by pre-treatment with Xanthorrhizol in a dose-dependent manner. The topical application of Xanthorrhizol after the induction of papillomas with hyperplasia and dysplasia also potently inhibited ODC expression.
(R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
(R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚
生產(chǎn)廠家
30199-26-9, (R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚 相關(guān)搜索:
- 抑制劑
- 黃藥醇
- 黃藥唑
- XANTHORRHIZOL,ANTIOXIDANT AGENT
- 黃根醇
- 束骨姜黃醇
- (R)-5-(1,5-二甲基-4-己烯基)-鄰甲酚
- 30199-26-9
- Xanthorrhizol, Antioxidant agent
- Xanthorrhizol,inhibit,Bacterial,Inhibitor
- Phenol, 5-[(1R)-1,5-dimethyl-4-hexen-1-yl]-2-methyl-
- 2-methyl-5-[(2R)-6-methylhept-5-en-2-yl]phenol
- (R)-(-)-Xanthorrhizol
- (-)-Xanthorrizol
- XANTHORRHIZOL(RG)
- Phenol, 5-(1,5-dimethyl-4-hexenyl)-2-methyl-, (-)-
- Einecs 250-090-2
- (R)-5-(1-5-Dimethyl-4-hexenyl)-2-methylphenol
- 5-[(R)-1,5-Dimethyl-4-hexenyl]-2-methylphenol
- 2-Methyl-5-[(R)-1,5-dimethyl-4-hexenyl]phenol
- (R)-Xanthorrizol
- Xanthorrhizol from Cucuma xanthorrhiza
- (R)-5-(1,5-dimethyl-4-hexenyl)-o-cresol
- Phenol, 5-(1,5-dimethyl-4-hexenyl)-2-methyl-, (R)-
- o-Cresol, 5-(1,5-dimethyl-4-hexenyl)-, (-)-
- 5-(1,5-Dimethyl-4-hexenyl)-2-methylphenol
- XANTHORRHIZOL