(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
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- CAS-Nr.
- 127910-31-0
- Englisch Name:
- (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
- Synonyma:
- CGP 37849;CGP 37849;CGP-37849;CGP37849;CGP 37849, competitive NMDA antagonist;dl-2-amino-4-methyl-5-phosphono-3-*pentenoic acid;(E)-2-Amino-4-methyl-5-phosphonopent-3-enoic acid;(3E)-2-Amino-4-methyl-5-phosphono-3-pentanoic acid;(E)-(±)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID;3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (3E)-;(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
- CBNumber:
- CB0334453
- Summenformel:
- C6H12NO5P
- Molgewicht:
- 209.14
- MOL-Datei:
- 127910-31-0.mol
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(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Eigenschaften
- Siedepunkt:
- 523.1±60.0 °C(Predicted)
- Dichte
- 1.506±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at +4°C
- L?slichkeit
- H2O: ≥2mg/mL (warmed)
- Aggregatzustand
- powder
- pka
- 1.83±0.10(Predicted)
- Farbe
- white to beige
- Wasserl?slichkeit
- H2O: 100mM
- InChI
- 1S/C6H12NO5P/c1-4(3-13(10,11)12)2-5(7)6(8)9/h2,5H,3,7H2,1H3,(H,8,9)(H2,10,11,12)/b4-2+
- InChIKey
- BDYHNCZIGYIOGJ-DUXPYHPUSA-N
- SMILES
- C\C(CP(O)(O)=O)=C/C(N)C(O)=O
(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
CGP 37849 is a potent antagonist at NMDA receptors which results in anticonvulsant activity (1). In addition, it may antagonize NMDA-antagonistic induced antianxiety effects (2).
Biologische Aktivit?t
Potent, selective and competitive NMDA receptor antagonist (K i = 35 nM). Anticonvulsive following oral administration in vivo .
(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 66)Lieferanten
- dl-2-amino-4-methyl-5-phosphono-3-*pentenoic acid
- (3E)-2-Amino-4-methyl-5-phosphono-3-pentanoic acid
- (E)-2-Amino-4-methyl-5-phosphonopent-3-enoic acid
- CGP 37849
- (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
- (E)-(±)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
- CGP 37849;CGP-37849;CGP37849
- 3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (3E)-
- CGP 37849, competitive NMDA antagonist
- 127910-31-0
- C6H12NO5P
- Glutamate receptor
- Glutamate
