(S)-ropivacaine hydrochloride hydrate
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- CAS-Nr.
- 132112-35-7
- Englisch Name:
- (S)-ropivacaine hydrochloride hydrate
- Synonyma:
- ROPIVACAINE HCL;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;Ropivacaine hydrochloride hydrate;Ropivacaine Hcl monohydrate;LEA-103;LEA-103 HCl;Ropivacaine HCI;S-ROPIVACAINE HCL;Ropivacaine HCl.H2O;Ropivacaine HCl (mono)
- CBNumber:
- CB0369811
- Summenformel:
- C17H26N2O.ClH.H2O
- Molgewicht:
- 328.88
- MOL-Datei:
- 132112-35-7.mol
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(S)-ropivacaine hydrochloride hydrate Eigenschaften
- Schmelzpunkt:
- 267-269°C
- alpha
- D20 -7.28° (c = 2 in water)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: soluble5mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to off-white
- Optische Rotation
- [α]/D -9 to -12, c = 1 in methanol
- Wasserl?slichkeit
- H2O: 5mg/mL, clear
- InChI
- InChI=1/C17H26N2O.ClH.H2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H;1H2/t15-;;/s3
- InChIKey
- VSHFRHVKMYGBJL-CKUXDGONSA-N
- SMILES
- [C@H]1(CCCCN1CCC)C(=O)NC1=C(C)C=CC=C1C.O.Cl |&1:0,r|
- CAS Datenbank
- 132112-35-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T,Xi |
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| R-S?tze: |
26/27/28-41 |
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| S-S?tze: |
22-36/37/39-45-39-26 |
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| RIDADR |
UN 2811 6.1 / PGIII |
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| WGK Germany |
3 |
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| HS Code |
2933399090 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Eye Dam. 1 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H318 |
Verursacht schwere Augensch?den. |
Schwere Augensch?digung |
Kategorie 1 |
Achtung |
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P280, P305+P351+P338, P310 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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(S)-ropivacaine hydrochloride hydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Beschreibung
(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers.
In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.
Chemische Eigenschaften
White Solid
Verwenden
Ropivacaine hydrochloride monohydrate has been used as an analyte in tandem mass spectrometry and as an amide-based local anaesthetic to test its effect on breast cancer cell methylation.
Definition
ChEBI: The monohydrate form of (S)-ropivacaine hydrochloride.
Allgemeine Beschreibung
Ropivacaine has lidocaine-related structure with tertiary amine side chains.It is a pure
S(-)enantiomer with a propyl group on the piperidine nitrogen atom.
(S)-ropivacaine hydrochloride hydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(S)-ropivacaine hydrochloride hydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 413)Lieferanten
132112-35-7()Verwandte Suche:
- (S)-1-propyl-2',6'-dimethylanilinoformoxylpiperidine monohydrochloride monohydrate
- (S)-1-propyl-2',6'-dimethylanilinoformoxylpiperidine,monohydrochloride,monohydrate
- (S)-Ropivaxaine hydrochloride
- (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
- (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide Hydrochloride Hydrate
- LEA-103
- (S)-ropivacaine hydrochloride hydrate
- Ropivacaine Hydrochloride (200 mg)
- 1-methy1-1h-tetrazol-5-ylthiol
- (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohydrate
- Ropivacaine Hydrochloride, USP
- Ropivacaine-(S) Hydrochloride
- Ropivacaine HCl.H2O
- LEA-103 HCl
- 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, hydrochloride (1:1), (2S)-
- Ropivacaine hydrochloride
(S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
- (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride monohydrate
- Naropin hydrochloride monohydrate
- S-ROPIVACAINE HCL
- (S)-ROPIVACAINE HYDROCHLORIDE
- ROPIVCACAINE HYDROCHLORIDE
- Ropivacaine Hydrochloride (1605500)
- Ropivacaine hydrochloride Naropin
- Ropivacaine hydrochloride USP/EP/BP
- (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride hydrate
- Ropivacaine HCl hydrate
- Ropivacaine HCI
- 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, hydrochloride, hydrate (1:1:1), (2S)-
- Ropivacaini Hydrochloridum Monohydricum
- (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-Piperidinecarboxamide hydrochloride hydrate (1:1:1)
- Ropivacaine HCl (mono)
- Ropivacaine HCl H2O
IP/USP/BP/EP
- Ropivacaine hydrochloride monohydrate, 10 mM in DMSO
- (2S)-N-(2,6-Dimethylphenyl)-1-propyl-piperidin-2-carboxamide HCl hydrate (1:1:1)
- Ropivacaine Hcl monohydrate
- ROPIVACAINE HCL
- ROPIVACAINE HYDROCHLORIDE MONOHYDRATE
- Ropivacaine hydrochloride hydrate
- 132112-35-7
- 13112-35-7
- CAS NO.98717-15
- 132115-35-7
- C17H26N2OxHCL
- C17H26N2OHCl
- C17H26N2OHCLH2O
- C17H28N2O2HCl
- C17H26N2O2HClH2O
- C17H26N2OClHH2O
- Inhibitors
- Chiral Reagents
- Intermediates & Fine Chemicals
- Pharmaceuticals
- API
- 132112-35-7
