QX-314
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- CAS-Nr.
- 21306-56-9
- Englisch Name:
- QX-314
- Synonyma:
- LIDOCAINE N-ETHYL BROMIDE;QX-314;QX-314.Br;QX 314 BROMIDE;QX 314, 10 mM in DMSO;Lidocaine N-ethyl bromid;Lidocaine N-ethyl bromide;QX-314 - CAS 21306-56-9 - Calbiochem;QX 314 BROMIDE,LIDOCAINE N-ETHYL BROMID;QX-314 bromide (N-Ethyllidocaine bromide)
- CBNumber:
- CB0421458
- Summenformel:
- C16H27N2O+
- Molgewicht:
- 263.4
- MOL-Datei:
- 21306-56-9.mol
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QX-314 Eigenschaften
- Schmelzpunkt:
- 220 - 222°C
- storage temp.
- Desiccate at RT
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- lyophilized solid
- Farbe
- White to Off-White
- Wasserl?slichkeit
- water: 3mg/mL
- Specific Activity
- 40-60 Ci/mmol
- Solvent
- Ethanol:water (1:1)
- Concentration
- 1 mCi/ml
- Major Application
- forensics and toxicology
pharmaceutical (small molecule)
veterinary
- InChI
- 1S/C16H26N2O.BrH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H
- InChIKey
- DLHMKHREUTXMCH-UHFFFAOYSA-N
- SMILES
- [Br-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C
QX-314 Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
Blocker of voltage-activated sodium channels
Biologische Aktivit?t
Membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na + channels. Intracellular QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons.
QX-314 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
QX-314 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 96)Lieferanten
21306-56-9()Verwandte Suche:
- 2-[(2,6-Dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium
- QX-314;LIDOCAINE N-ETHYL BROMIDE;N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE
- QX-314.Br
- QX-314 bromide (N-Ethyllidocaine bromide)
- N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE
- N-(2,6-DIMETHYLPHENYL)ACETAMIDE-2-TRIETHYLAMMONIUM BROMIDE
- QX-314
- QX 314 BROMIDE
- LIDOCAINE N-ETHYL BROMIDE (QUATERNARY SALT)
- QX-314 - CAS 21306-56-9 - Calbiochem
- Lidocaine N-ethyl bromid
- Lidocaine N ethyl bromide,Lidocaine Nethyl bromide
- Ethanaminium,2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxo-
- QX-314 bromide (N-Ethyllidocaine bromide), Na+ channel blocker
- QX-314 bromide (N-Ethyllidocaine bromide) (mM/ml), Na+ channel blocker
- QX 314, 10 mM in DMSO
- Lidocaine N-ethyl bromide
- QX 314 BROMIDE,LIDOCAINE N-ETHYL BROMID
- LIDOCAINE N-ETHYL BROMIDE
- 21306-56-9
- C16H27BrN2O
- C16H27N2OBr
- C16H27N2O
- A quaternary derivative of lidocaine that is not membrane permeable. Blocks both fast Na+-dependent action potentials and voltage-dependent, non-inactivating Na+ conductance.
- Analytical Chromatography Product Catalog
- Analytical Standards
- Alphabetic
- Sodium channel
- Ion Channels
