Droxicam
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- CAS-Nr.
- 90101-16-9
- Englisch Name:
- Droxicam
- Synonyma:
- E-318;E-3128;Droxar;Ombolan;Dobenam;DROXICAM;Droxicamum;Droxicam USP/EP/BP;5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione;5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
- CBNumber:
- CB0664772
- Summenformel:
- C16H11N3O5S
- Molgewicht:
- 357.34
- MOL-Datei:
- 90101-16-9.mol
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Droxicam Eigenschaften
- Schmelzpunkt:
- 259-261°
- Siedepunkt:
- 554.7±60.0 °C(Predicted)
- Dichte
- 1.68±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly, Heated)
- pka
- 3.80±0.19(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Off-White to Pale Yellow
- CAS Datenbank
- 90101-16-9
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Toxizit?t |
LD50 orally in male, female mice, and male, female rats: 6192, 8841, 1434, 1994 mg/kg (Soler, 1986) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitssch?dlich bei Einatmen. |
Akute Toxizit?t inhalativ |
Kategorie 4 |
Warnung |
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P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Droxicam Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Droxicam is an orally-active prodrug of piroxicam useful in the treatment of
spinal osteoarthritis. Although it has a pharmacological profile comparable to
piroxicam, droxicam's experimental ulcerogenic effect is ten times less. In animal
studies droxicam is also reported to have analgesic and antipyretic activities, with no
cardiovascular or respiratory effects.
Verwenden
Droxicam is a non-steroidal anti-inflammatory drug.
Definition
ChEBI: An organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respe
tively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.
Weltgesundheitsorganisation (WHO)
Droxicam is authorized to be marketed in many European
countries. Although droxicam is metabolized to piroxicam, it is considered that the risk of hepatic damage differs from that shown by other NSAIDs products,
including piroxicam.
Droxicam Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Droxicam Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 49)Lieferanten
90101-16-9()Verwandte Suche:
- DROXICAM
- 5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
- 5-Methyl-3-(pyridin-2-yl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
- E-318
- 5-Methyl-3-(2-pyridinyl)-2H，5 H-1，3-oxaZino[5，6-c][1，2]benzothiazine-2，4(3H)-dione-6，6-dioxide
- Dobenam
- Droxar
- E-3128
- Ombolan
- 5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-dioxide
- 5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino-[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-diox
- 5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione
- 2H,5H-1,3-Oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione, 5-methyl-3-(2-pyridinyl)-, 6,6-dioxide
- Droxicam USP/EP/BP
- Droxicamum
- 5-Methyl-3-(pyridin-2-yl)-3-hydro-2H,5H-benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4-dione 6,6-dioxide
- 90101-16-9
- C16H11N3O5S
