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Droxicam

Droxicam Struktur
90101-16-9
CAS-Nr.
90101-16-9
Englisch Name:
Droxicam
Synonyma:
E-318;E-3128;Droxar;Ombolan;Dobenam;DROXICAM;Droxicamum;Droxicam USP/EP/BP;5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione;5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
CBNumber:
CB0664772
Summenformel:
C16H11N3O5S
Molgewicht:
357.34
MOL-Datei:
90101-16-9.mol

Droxicam Eigenschaften

Schmelzpunkt:
259-261°
Siedepunkt:
554.7±60.0 °C(Predicted)
Dichte
1.68±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO (Slightly), Methanol (Slightly, Heated)
pka
3.80±0.19(Predicted)
Aggregatzustand
Solid
Farbe
Off-White to Pale Yellow
CAS Datenbank
90101-16-9
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Toxizit?t LD50 orally in male, female mice, and male, female rats: 6192, 8841, 1434, 1994 mg/kg (Soler, 1986)
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H332 Gesundheitssch?dlich bei Einatmen. Akute Toxizit?t inhalativ Kategorie 4 Warnung P261, P271, P304+P340, P312
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Droxicam Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Droxicam is an orally-active prodrug of piroxicam useful in the treatment of spinal osteoarthritis. Although it has a pharmacological profile comparable to piroxicam, droxicam's experimental ulcerogenic effect is ten times less. In animal studies droxicam is also reported to have analgesic and antipyretic activities, with no cardiovascular or respiratory effects.

Verwenden

Droxicam is a non-steroidal anti-inflammatory drug.

Definition

ChEBI: An organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respe tively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.

Weltgesundheitsorganisation (WHO)

Droxicam is authorized to be marketed in many European countries. Although droxicam is metabolized to piroxicam, it is considered that the risk of hepatic damage differs from that shown by other NSAIDs products, including piroxicam.

Droxicam Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Droxicam Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 48)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED
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571-89925085
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526763801@qq.com China 9459 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 17714375163
cfzhang@aikonchem.com China 19906 55
Finetech Industry Limited 027-87465837 19945049750
sales@finetechnology-ind.com China 9345 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9804 58

90101-16-9()Verwandte Suche:


  • DROXICAM
  • 5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
  • 5-Methyl-3-(pyridin-2-yl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
  • E-318
  • 5-Methyl-3-(2-pyridinyl)-2H,5 H-1,3-oxaZino[5,6-c][1,2]benzothiazine-2,4(3H)-dione-6,6-dioxide
  • Dobenam
  • Droxar
  • E-3128
  • Ombolan
  • 5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-dioxide
  • 5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino-[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-diox
  • 5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione
  • 2H,5H-1,3-Oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione, 5-methyl-3-(2-pyridinyl)-, 6,6-dioxide
  • Droxicam USP/EP/BP
  • Droxicamum
  • 5-Methyl-3-(pyridin-2-yl)-3-hydro-2H,5H-benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4-dione 6,6-dioxide
  • 90101-16-9
  • C16H11N3O5S
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