N-Acetyl-3-phenyl-L-alanin
|
|
|
- CAS-Nr.
- 2018-61-3
- Bezeichnung:
- N-Acetyl-3-phenyl-L-alanin
- Englisch Name:
- N-Acetyl-L-phenylalanine
- Synonyma:
- AC-PHE-OH;Ac-L-Phe-OH;Acetylphenylalanine;ACETYL-L-PHENYLALANINE;L-Phenylalanine, N-acetyl-;N-Ac-L-Phe-OH;(2S)-2-Acetamido-3-phenylpropanoic acid;Ac-L-Phe;NSC 45699;H-Ac-Phe-OH
- CBNumber:
- CB1170986
- Summenformel:
- C11H13NO3
- Molgewicht:
- 207.23
- MOL-Datei:
- 2018-61-3.mol
|
N-Acetyl-3-phenyl-L-alanin Eigenschaften
- Schmelzpunkt:
- 171-173 °C(lit.)
- alpha
- 40 º (c=1,methanol)
- Siedepunkt:
- 346.25°C (rough estimate)
- Dichte
- 1.1878 (rough estimate)
- Brechungsindex
- 40 ° (C=5, MeOH)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Solubility in methanol (almost transparency). Soluble in acetone and ethanol (20 mg/ ml).
- pka
- 3.56±0.10(Predicted)
- Aggregatzustand
- Fine Crystalline Powder or Needles
- Farbe
- White to off-white
- Optische Rotation
- [α]22/D +40.0°, c = 1 in methanol
- Major Application
- peptide synthesis
- InChI
- 1S/C11H13NO3/c1-8(13)12-10(11(14)15)7-9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H,12,13)(H,14,15)/t10-/m0/s1
- InChIKey
- CBQJSKKFNMDLON-JTQLQIEISA-N
- SMILES
- CC(=O)N[C@@H](Cc1ccccc1)C(O)=O
- CAS Datenbank
- 2018-61-3(CAS DataBase Reference)
- NIST chemische Informationen
- L-phenylalanine, n-acetyl-(2018-61-3)
- EPA chemische Informationen
- L-Phenylalanine, N-acetyl- (2018-61-3)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
|
|
| WGK Germany |
3 |
|
|
| TSCA |
TSCA listed |
|
|
| HS Code |
29242990 |
|
|
| Speicherklasse |
11 - Combustible Solids |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
|
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
|
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
|
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
N-Acetyl-3-phenyl-L-alanin Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white to off-white fine cryst. powder or needles
Verwenden
It is an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of aspartame. It is applied as an antidepressant.
Definition
ChEBI: The N-acetyl derivative of L-phenylalanine.
Allgemeine Beschreibung
N-Acetyl-L-phenylalanine is an acetyl analog of L-phenylalanine. It is widely used as a reactant to synthesize methyl or ethyl esters of
N-acetyl-L-phenylalanine, which are employed as versatile building blocks in peptide synthesis.
l?uterung methode
N-Acetyl-L-phenylalanine is recrystallised from H2O, 20% MeOH/H2O, or CHCl3; dry and store it at 4o. The (DL)-isomer crystallises from H2O, Me2CO, EtOAc, or CHCl3 with m 152-154o and the solubilities in w% at 25o are 0.73 (H2O), 4.3 (Me2CO), 0.79 (EtOAc) and 0.34 (CHCl3) [Kerr & Niemann J Org Chem 23 893 1958, Overby & Ingersoll J Am Chem Soc 73 3363 1951, L: Fu et al. J Am Chem Soc 76 6057 1954, Bender & Glasson J Am Chem Soc 81 1591 1959]. [Beilstein 14 I 238, 4 IV 1575.]
N-Acetyl-3-phenyl-L-alanin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-Acetyl-3-phenyl-L-alanin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 497)Lieferanten
2018-61-3(N-Acetyl-3-phenyl-L-alanin)Verwandte Suche:
- (2S)-2-(Acetylamino)-3-phenylpropanoic acid
- (2S)-2-(Acetylamino)-3-phenylpropionic acid
- (S)-α-(Acetylamino)benzenepropanoic acid
- (αS)-α-(Acetylamino)benzenepropanoic acid
- N-Ac-Phenylalanine
- L-2-(ACETYLAMINO)-3-PHENYLPROPANOIC ACID
- AC-PHENYLALANINE
- N-acetyl-3-phenyl-L-alanine
- N-Acetyl-L-plhenylalanine
- N-ACETYL-L-PHENYLALANINE SIGMA GRADE
- N-Acetyl-L-phenylalanine, 99+%
- (2S)-acetylamino-3-phenyl-propanoic acid
- N-ACETYL-L-PHENYLALANINE:AC-PHE-OH
- N-alpha-Actetyl-L-phenylalanine
- N-ACETYL-L-PHENYLALANINE
- (2S)-N-ACETYL-L-PHENYLALANINE
- N-propionyl leucine
- (S)-2-AcetaMido-3-phenylpropanoic acid
- N-Acetyl-L-phenylalanine ReagentPlus(R), 99%
- Ac-Phe-OH ( N-acetyl-L-phenylalanine )
- N-Acetyl-L-phenylalanine Vetec(TM) reagent grade, 98%
- (S)-2-(N-phenylacetamido)propanoic acid
- Acetyl-L-phenylalanine≥ 99% (HPLC)
- N-ALPHA-ACETYL-L-PHENYLALANINE
- Alanine, N-acetyl-3-phenyl-, L-
- L-N-Acetylphenylalanine
- n-acetyl-l-phenylalanin
- Amino Acid Impurity 45
- (2S)-2-acetamido-3-phenylpropanoate
- N-Acetyl-L-phenylalanine >
- N-Acetyl-L-phenylalanine USP/EP/BP
- N-acetyl-laevo-phenyl alanine
- NSC 45699
- Acetylphenylalanine
- L-Phenylalanine, N-acetyl-
- N-Ac-L-Phe-OH
- Ac-L-Phe
- N-Acetyl-L-phenylalanine
- (2S)-2-Acetamido-3-phenylpropanoic acid
- AC-PHE-OH
- ACETYL-L-PHENYLALANINE
- Ac-L-Phe-OH
- H-Ac-Phe-OH
- N-Acetyl-l-phenalanine
- 2018-61-3
- C6H5CH2CHNHCOCH3CO2H
- Amino Acid Derivatives
- Peptide Synthesis
- Phenylalanine
- Specialty Synthesis
- chiral
- Amino Acids Derivatives
- Amino Acid Derivatives
- Amino Acids
- N-Acetyl-Amino acid series
- Amino Acid Derivatives
- Peptide Synthesis
- Phenylalanine
