2-Aminooctadec-4-en-1,3-diol
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- CAS-Nr.
- 123-78-4
- Bezeichnung:
- 2-Aminooctadec-4-en-1,3-diol
- Englisch Name:
- D-ERYTHRO-SPHINGOSINE
- Synonyma:
- SPHINGOSINE;D-SPHINGOSINE;Sphingosine (d18:1);CEREBROSIDE;4-SPHINGENINE;(2S,3R,E)-2-aMinooctadec-4-ene-1,3-diol;TRANS-D-ERYTHRO-2-AMINO-4-OCTADECENE-1,3-DIOL;Sphingenine;SPHINGOSINE, D-ERYTHRO;(2S,3R,4E)-2-amino-4-Octadecene-1,3-diol
- CBNumber:
- CB1262764
- Summenformel:
- C18H37NO2
- Molgewicht:
- 299.49
- MOL-Datei:
- 123-78-4.mol
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2-Aminooctadec-4-en-1,3-diol Eigenschaften
- Schmelzpunkt:
- 74.2-78.1 °C
- Siedepunkt:
- 440.8°C (rough estimate)
- Dichte
- 0.9758 (rough estimate)
- Brechungsindex
- 1.5000 (estimate)
- storage temp.
- -20°C
- L?slichkeit
- chloroform: 20 mg/mL, clear, colorless to very faintly yellow
- pka
- 11.80±0.45(Predicted)
- Aggregatzustand
- Powder or Waxy Solid
- Farbe
- White to cream
- Biologische Quelle
- synthetic
- Merck
- 14,8747
- BRN
- 1727294
- Stabilit?t:
- Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
- InChI
- 1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
- InChIKey
- WWUZIQQURGPMPG-KRWOKUGFSA-N
- SMILES
- OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
- CAS Datenbank
- 123-78-4
2-Aminooctadec-4-en-1,3-diol Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White Crystalline Solid
Verwenden
D-erythro-Sphingosine is used to inhibits protein kinase C and calmodulin-dependent enzymes, induces apoptosis. And also used to constituent of cell membranes.
Definition
cerebroside: Any one of a class ofglycolipids in which a single sugarunit is bound to a sphingolipid. The most commoncerebrosides are galactocerebrosides,containing the sugar group galactose;they are found in the plasma membranesof neural tissue and are abundantin the myelin sheaths ofneurones.
Allgemeine Beschreibung
Sphingosine (d18:1) is a spingoid base present in plant and animals. It has 2-amino-1,3-diol functionality and its extraction from animal tissue is laborious. Sphingosine (d18:1) synthesis is performed by chirospecific method using D-galactose.
Biologische Aktivit?t
Inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.
l?uterung methode
D-Sphingosine is purified by recrystallisation from EtOAc, Et2O or pet ether (60-80o). It is insoluble in H2O but is soluble in Me2CO, EtOH and MeOH. It has IR bands at 1590 and 875 cm-1, and is characterised as the tribenzoate m 122-123o (from 95% EtOH). [Tipton Biochemical Preparations 9 127 1962.]
2-Aminooctadec-4-en-1,3-diol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Aminooctadec-4-en-1,3-diol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 262)Lieferanten
123-78-4(2-Aminooctadec-4-en-1,3-diol)Verwandte Suche:
- SPHINGOSINE, C18 CHAIN
- TRANS D-THREO-SPHINGOSINE
- TRANS D-ERYTHRO-SPHINGOSINE
- BRAIN SPHINGOSINE
- BRAIN, BOVINE
- EGG SPHINGOSINE
- D-SPHINGOSINE (BOVINE)
- D-ERYTHRO-SPINGHOSINE
- D-ERYTHRO-SPHINGASINE (EGG)
- D-ERYTHRO-SPHINGOSINE
- D-ERYTHRO-SPHINGOSINE, BOVINE
- D-ERYTHRO-SPHINGOSINE, BOVINE BRAIN
- D-ERYTHRO-SPHINGOSINE (BRAIN)
- 2-AMINO-4-OCTADECENE-1,3-DIOL
- D-SPHINGOSINE FROM BOVINE BRAIN &
- D-SPHINGOSINE FROM BOVINE BRAIN*CEREBROS IDES
- D-SPHINGOSINE FROM BOVINE BRAIN SPHINGOMYELIN*
- 2-aminooctadec-4-ene-1,3-diol
- D-ERYTHRO-SPHINGOSINE (1,2-13C2, 1,1-D2)
- D-Sphingosine (from bovine brain sphinogomyelin)
- 4-Sphingenine, trans-D-erythro-2-Amino-4-octadecene-1,3-diol
- D-erythro-Sphingosine (synthetic)
- D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL
- D-erythro-Sphingosine, synthetical
- (2S,3R,E)-2-Amino-4-octadecene-1,3-diol
- C18-Sphingosine
- erythro-4-Sphingenine
- D-erythro-Sphingosine C-18
- Erythrosphingosine
- trans-4-Sphingenine
- D-erythro-Sphingosine, synthetical, 99+%
- D-Sphingosine: trans-D-erythro-2-Amino-4-octadecene-1,3-diol
- (E,2S,3R)-2-Aminooctadec-4-Ene-1,3-Diol
- D-erythro-Sphingosine(DES)
- D-ERYTHRO-SPHINGOSINE;SPHINGOSINE (D18:1)
- D-erythro-Sphingosine, 99+%
- D-Sphingenine
- D-erythro-Sphingosine, Free Base, High Purity - CAS 123-78-4 - Calbiochem
- D-Sphingosine >
- erythro-C18-Sphingosine
- 4-Octadecene-1,3-diol, 2-amino-, (2S,3R,4E)-
- D-erythro-Sphingosine (Erythrosphingosine)
- SPHINGOSINE, D-ERYTHRO
- Sphingenine
- 2-Aminooctadec-4-en-1,3-diol
- D-Sphingosine/(2S,3R,E)-2-Amino-4-octadecene-1,3-diol
- D-Sphingosine/D-erythro-Sphingosine
- D-ERYTHRO-SPHINGOSINE, 10 mM in DMSO
- D-erythro-Sphingosine, Free Base, High Purity
- D-Sphingosine
- Sphingosine - Bio-X ?
- Sphingosinum
- Sphingosine，D-ERYTHRO-SPHINGOSINE，D-Sphingosine
- (2S,3R,E)-2-aminodecaoctacarbon-4-ene-1,3-diol
- (2S,3R,E)-2-aMinooctadec-4-ene-1,3-diol
- (2S,3R,4E)-2-amino-4-Octadecene-1,3-diol
- 4-SPHINGENINE
- CEREBROSIDE
