tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

tert-Butyl [(1R,2S,5S)-2-Amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate Oxalate is a starting material and useful building block of various pharmaceuticals.

Verwenden

Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate is also called EthanediaMide iMpurity A. It is a starting material and useful component of various pharmaceuticals. As an organic synthesis intermediate and pharmaceutical intermediate. It could be used in the synthesis and research of the EthanediaMide.

Synthese

Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate is prepared by the reaction of benzyl N-[(1S,2R,4S)-2-{[(tert-butoxy)carbonyl]amino}-4-(dimethylcarbamoyl)cyclohexyl]carbamate and Oxalic Acid. The steps are as follows:
Pd-C (230 mg) was added to a solution (35 mL) of benzyl t-butyl{(1S,2R,4S)-4-[(dimethylamino)carbonyl]cyclohexan-1,2-diyl}biscarbamate (2.3 g) in ethanol, and the mixture was stirred in a hydrogen atmosphere for 16 hours. Pd-C was removed by filtration, and the filtrate was concentrated under reduced pressure. Ethyl acetate (20 mL) and anhydrous oxalic acid (493.6 mg) were added to the residue, followed by stirring at room temperature for 17 hours. The formed crystals were recovered by filtration, to thereby yield 1.93 g of the Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate.

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Eaglech（shanghai）Pharmaceutical Co., Ltd	+86-2160290089 +86-13884467586	eagpharm@gmail.com	China	116	58
ZHUHAI HRD PHARMACEUTICAL CO., LTD.	+8613326687259	sales@hrdpharm.com	China	60	58
Shanghai Joiny Pharmaceutical Co.,LTD	+86-13681955282 +86-13681955282;	gyd@joiny-pharma.com	China	402	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	1006	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21586	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58

1210348-34-7()Verwandte Suche:

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• (2-Azido-5-diMethylcarbaMoyl-cyclohexyl)-carbaMic acid tert-butyl esteroxalic acid
• 2EthanediaMide iMpurity A
• tert-Butyl [(1R,2S,5S)-2-aMino-5-[(diMethylaMino)carbonyl]cyclohexyl]carbaMate oxalate
• tert-Butyl [(1R,2S,5S)-2-aMino-5-[(diMethylaMino)carbonyl]cyclohexyl]carbaMate oxalate(for Edoxaban)
• tert-butyl N-[(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate
• (1S,2R,4S)-2-[(tert-Butoxycarbonyl)Amino ]-4-[( dimethylamino)carbonyl]- cyclohexyl ammonia oxalate
• Edoxaban Intermediate II
• tert-butyl N-[(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate oxalate
• Edoxaban Impurity 15 Oxalate
• Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalate
• tert-butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate oxalic acid
• Edoxaban-1
• (1S,2R,4S)-2-[(tert-Butoxyc
• tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate(For export only)
• (1S,2R,4S)-2-[(tert-Butoxycarbonyl]- cyclohexyl ammonia oxalate
• (1s, 2R, 4S) - 1-amino-4 - (dimethylaminocarbonyl) - cyclohexyl-2-carbamate tert butyl oxalic acid
• Idosaiban intermediate 2
• Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalic acid
• N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-Carbamic acid, 1,1-dimethylethyl ester, ethanedioate (1:1)
• ert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamateoxalate
• EBD3313800
• Tertiary Butyl [1R,2S, 5S]-2-Amino-5-Dimethylcarboyl) Cyclohexylcarbamate Oxalate
• tert-butyl (1R,2S,5S)-5-(dimethylcarbamoyl)-2-aminocyclohexylcarbamate oxalate
• Yidu Saban Impurity A
• Edoxaban Impurity A（Oxalate）
• [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate
• tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate carbamic acid
• Tert-Butyl((1R,2S,5S)-2-amino-5-(dimethyl- carbamoyl)cyclohexyl)carbarmate oxalate
• Edoxaban Impurity 9 Oxalate
• N-[(1R,2S,5S)-2-azido-5-(dimethylcarbamoyl)cyclohexyl]-N-tert-butylcarbamate
• (1S,2R,4S)-1-Amino-4-(dimethylaminocarbonyl)-cyclohexyl-2-carbamicacidtert-butylesteroxalate
• teri-Butyl [(1R,2S,5S)-2-amino-5-(dimethvlcarbamovl'cvclohexvllcarbamate oxalate
• tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyllcyclohexyllcarbamate oxalate
• tert-Butyl [(1R,2S,5S)-2-amino -5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate (Intermediate of Edoxaban mesylate)
• 2-(4-Cyanophenylamino)acetic acid (Intermediate of Dabigatran etexilate mesylate)
• 2-Methyl-2-propanyl [(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate ethanedioate (1:1)
• EthanediaMide iMpurity A
• EthanediaMide iMpurity A/Edoxaban Intermediate II
• oxalic acid tert-butyl N-[(1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexyl]carbaMate
• tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate oxalate
• Tert-butyl(1R, 2S, 5S)-2-amino-5-((dimethylamino)carbonyl)cyclohexylcarbamate oxalic acid
• Edoxaban Intermediate (SAV-10 Oxalate)
• 1210348-34-7
• 365998-36-8
• C14H27N3O3C2H2O4