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MMP-2/MMP-9 Inhibitor I

MMP-2/MMP-9 Inhibitor I Struktur
193807-58-8
CAS-Nr.
193807-58-8
Englisch Name:
MMP-2/MMP-9 Inhibitor I
Synonyma:
MMP-2;COLLAGENASE D;MMP-1;COLLAGENASE, TYPE 2;MMPL;EC 3.4.24.7;EC 3.4.24.3;Collagese P;MMP-2, HUMAN;EC 3.4.24.24
CBNumber:
CB1309850
Summenformel:
C21H19NO4S
Molgewicht:
381.44
MOL-Datei:
193807-58-8.mol

MMP-2/MMP-9 Inhibitor I Eigenschaften

Schmelzpunkt:
146-147 °C
Siedepunkt:
595.9±60.0 °C(Predicted)
Dichte
1.297±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
≤25mM in DMSO
pka
3.26±0.10(Predicted)
Aggregatzustand
powder
Farbe
light brown
Biologische Quelle
human
Wasserl?slichkeit
water: soluble
Specific Activity
≥600mU/mg protein
CAS Datenbank
193807-58-8

Sicherheit

Kennzeichnung gef?hrlicher B,Xi
R-S?tze: 36/37/38-42
S-S?tze: 23-26-36-24/25
WGK Germany  2
10-21
Speicherklasse 11 - Combustible Solids

MMP-2/MMP-9 Inhibitor I Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R42:Sensibilisierung durch Einatmen m?glich.

S-S?tze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Matrix metalloproteinase-2 (MMP2) human has been used:
  • As a standard in zymography to measure gelatinolytic activity of MMP2.
  • In enzymatic method for dissociation of brain tissue to single cells.

Allgemeine Beschreibung

Matrix metalloproteinase-2 (MMP-2) also known as gelatinase or type IV collagenase is a 72kDa protein. MMP-2 is a member of matrix metalloproteinase (MMP) family of enzymes. Basic structure of MMP2 contains signal peptide domain that targets the enzyme for secretion, the pro-peptide domain, which is removed when the enzyme is activated and the catalytic site containing gelatin-binding domain.

Biochem/physiol Actions

Matrix Metalloproteinase-2 (MMP-2) cleaves gelatin, type IV, V, VII, X, and XI collagens, fibronectin, elastin, laminin, proteoglycans and a range of non extracellular matrix (ECM ) components. MMP-2 cleaves native type I collagen to N-terminal and C-terminal fragments identical to those generated by interstitial collagenases. MMP2 and MMP9 play an essential role in matrix degradation and they are implicated in the maintenance of neovascularization. In mice, deletion or inhibition of MMP2 protects against myocardial rupture.

MMP-2/MMP-9 Inhibitor I Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


MMP-2/MMP-9 Inhibitor I Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 298)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19936 58
Creative Enzymes
1-516-855-7709
info@creative-enzymes.com United States 8748 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 20584 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19908 58
Aladdin Scientific

tp@aladdinsci.com United States 52923 58
TargetMol Chemicals Inc. 021-021-33632979 15002134094
marketing@targetmol.com China 8000 58
Chengdu RunZeBenTu Chemical Co., Ltd 13096311329 028-88469284 616445927
616445927@qq.com China 2874 50
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903
3008007409@qq.com China 89686 60

193807-58-8()Verwandte Suche:


  • Collagenase Type IV 72 kDa
  • Gelatinase, 72 kDa
  • Collagenase Type IV 72 kD
  • 72 Kd Gelatinase 72 Kd Type IV collagenase Gelatinase A
  • Matrix Metalloproteinase-2 human
  • PROENZYME MMP-2
  • PROGELATINASE A
  • MMP-1 PROENZYME
  • MMP-1, PROENZYME HUMAN RHEUMATOID SYNOVIAL FIBROBLAST
  • MMP-1, STABLE HUMAN FIBROBLASTS
  • MMP-1 ENZYME, HUMAN
  • MMP-1, HUMAN PROTEIN
  • MMPL
  • MMP-2, PROENZYME
  • MMP-2, PROENZYME HUMAN RHEUMATOID SYNOVIAL FIBROBLAST
  • MMP-2, PROENZYME MOUSE MACROPHAGE
  • MMP-2 ENZYME, HUMAN
  • MMP-2, HUMAN
  • TYPE IV COLLAGENASE
  • TYPE 1 COLLAGENASE
  • 72 KDA GELATINASE
  • 72 KDA GELATINASE, PROENZYME
  • 72 KDA TYPE IV COLLAGENASE
  • 72 KDA TYPE IV COLLAGENASE, PROENZYME
  • 72 KD GELATINASE
  • 72 KD TYPE IV COLLAGENASE
  • ACTIVE MMP-2 ENZYME
  • MATRIX METALLOPROTEINASE-1
  • MATRIX METALLOPROTEINASE 1, PROENZYME
  • MATRIX METALLOPROTEINASE-1, STABLE HUMAN FIBROBLASTS
  • MATRIX METALLOPROTEINASE 2
  • MATRIX METALLOPROTEINASE-2 (MOUSE FIBROBLASTS)
  • MATRIX METALLOPROTEINASE 2, PROENZYME
  • MATRIX METALLOPROTEINASE, PROENZYME
  • EC 3.4.24.7
  • EC 3.4.24.24
  • EC 3.4.24.3
  • EC: 3.4.24.3
  • COLLAGENASE-1
  • COLLAGENASE 1 PROENZYME
  • COLLAGENASE-1, STABLE HUMAN FIBROBLASTS
  • COLLAGENASE FORM II
  • COLLAGENASE (GRADE A)
  • 72 kD Gelatinase, 72 kD Type IV Collagenase, Gelatinase A, MMP-2
  • Matrix Metalloproteinase-2 from mouse fibroblasts
  • Collagenase-1, Interstitial Collagenase, MMP-1
  • Matrix Metalloproteinase-1, Stable from human fibroblasts
  • Matrix Metalloproteinase-2 from human fibroblasts
  • Matrix Metalloproteinase-2 from mouse
  • Matrix Metalloproteinase-1 human
  • Matrix Metalloproteinase-2 from rat fibroblasts
  • COLLAGENASE (GRADE B)
  • COLLAGENASE H
  • COLLAGENASE (72KDA TYPE IV) PROENZYME
  • COLLAGENASE AND PROTEASE INHIBITOR
  • COLLAGENASE B
  • COLLAGENASE N-2
  • COLLAGENASE, PROENZYME
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