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5-Methylcytidin

5-Methylcytidine Struktur
2140-61-6
CAS-Nr.
2140-61-6
Bezeichnung:
5-Methylcytidin
Englisch Name:
5-Methylcytidine
Synonyma:
4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidin-2(1H)-one;5-Me-Cr;NSC 363933;5-METHYLCYTIDINE;5-Methyicytidine;5-Methylcytidine>Cytidine, 5-Methyl-;Cytarabine EP Impurity G;5-METHYLCYTIDINE USP/EP/BP;RNA modified nucleoside m5C
CBNumber:
CB1352003
Summenformel:
C10H15N3O5
Molgewicht:
257.24
MOL-Datei:
2140-61-6.mol

5-Methylcytidin Eigenschaften

Schmelzpunkt:
212-215 °C (dec.) (lit.)
Siedepunkt:
537.5±60.0 °C(Predicted)
Dichte
1.79
Brechungsindex
15 ° (C=2, H2O)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
L?slichkeit
DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
pka
pK1:4.21 (25°C)
Aggregatzustand
Solid
Farbe
Off-White to Pale Beige
PH
4.3
Wasserl?slichkeit
water: 25mg/mL, clear, colorless
maximale Wellenl?nge (λmax)
287 (pH 0);277 (pH 7)
Stabilit?t:
Hygroscopic
InChI
InChI=1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1
InChIKey
ZAYHVCMSTBRABG-JXOAFFINSA-N
SMILES
OC[C@H]1O[C@@H](N2C=C(C)C(N)=NC2=O)[C@H](O)[C@@H]1O
CAS Datenbank
2140-61-6(CAS DataBase Reference)

Sicherheit

Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36-24/25
WGK Germany  3
HS Code  29389090
Speicherklasse 11 - Combustible Solids

5-Methylcytidin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

The methylation of carbon 5 in cytidine (m5C, 5-methylcytidine) has been identified as a widespread epitranscriptomic mark. 5-Methylcytidine is mostly found in tRNA and rRNA. 5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA and DNA for certain organisms. Roughly one to two residues of 5-methylcytidine occur in every 1,000 RNA residues. It has been used in epigenetics research, especially in studies involving DNA methylation processes involved in the establishment of genomic imprinting and the control of gene expression and differentiation.

Chemische Eigenschaften

White powder

Verwenden

5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.

Allgemeine Beschreibung

5-Methylcytidine is a component of RNA in Escherichia coli. It is present in the RNA of plant, animal and bacterial origin. It is one of the C derivative present in transfer RNA (tRNA).

5-Methylcytidin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


5-Methylcytidin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 230)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
16314854226; +8616314854226
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Hebei Chuanghai Biotechnology Co., Ltd
+86-15350571055
Sibel@chuanghaibio.com China 8738 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
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+86-15335185688
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Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14332 58
Antai Fine Chemical Technology Co.,Limited
18503026267
info@antaichem.com CHINA 9636 58
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000
marketing@targetmol.com United States 32466 58

2140-61-6(5-Methylcytidin)Verwandte Suche:


  • 5-METHYLCYTIDINE
  • 5-METHYLCYTIDINE, 98.0+%(LC)(T)
  • Cytidine, 5-Methyl-
  • 3: PN: US20060035254 PAGE: 63 claimed sequence
  • NSC 363933
  • 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidin-2-one
  • 5-Me-Cr
  • Cytarabine EP Impurity G
  • Cytarabine Impurity 17(Cytarabine EP Impurity G)
  • 5-Methylcytidine>
  • 5-METHYLCYTIDINE USP/EP/BP
  • 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one
  • 4-amino-5-methyl-1-β- D -ribofuranosylpyrimidin-2(1H)-one
  • 4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidin-2(1H)-one
  • 5-Methylcytidine,RNA modified nucleoside m5C
  • 5-Methyicytidine
  • 5-Methylcytidine, 10 mM in DMSO
  • RNA modified nucleoside m5C
  • 2140-61-6
  • Biochemicals and Reagents
  • BioChemical
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
  • Biochemistry
  • Nucleosides and their analogs
  • Nucleosides, Nucleotides & Related Reagents
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
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