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Cevimeline

Cevimeline Struktur
107233-08-9
CAS-Nr.
107233-08-9
Englisch Name:
Cevimeline
Synonyma:
Evoxac;AF-102B;SNI-2011;3R)-rel-;Hsdb 7286;Cevimeline;3]oxathiolane];AF-102B;FKS-508;CevimelineHClSalt;CeviMeline(Evoxac)
CBNumber:
CB1490161
Summenformel:
C10H17NOS
Molgewicht:
199.31
MOL-Datei:
107233-08-9.mol

Cevimeline Eigenschaften

Schmelzpunkt:
195-197°C
Siedepunkt:
308.5±42.0 °C(Predicted)
Dichte
1.19
storage temp. 
Sealed in dry,Store in freezer, under -20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
Powder
pka
9.51±0.40(Predicted)
CAS Datenbank
107233-08-9

Sicherheit

Giftige Stoffe Daten 107233-08-9(Hazardous Substances Data)

Cevimeline Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Off-White Solid

Verwenden

A muscarinic M1 and M3 receptor agonist. Sialagogue

Synthese

The synthesis of cevimeline commences with the epoxidation of the starting material 3-quinuclidinone (2) to yield the intermediate epoxide of 3-methylenequinuclidine (3). This reacts with thiol carboxylic acid RCOSH to form compound (4), which is subsequently converted to the intermediate 3-hydroxy-3-mercaptomethylquinuclidine (5) in the presence of acid or base. and finally purified via a one-pot process.
synthesis of CEVIMELINE, HYDROCHLORIDE SALT

Cevimeline Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cevimeline Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 98)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29640 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29812 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14332 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58
AFINE CHEMICALS LIMITED
+86-571-85134551
info@afinechem.com China 15080 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Guangzhou TongYi biochemistry technology Co.,LTD
+8613073028829
tongyibiochem@163.com China 2995 58

107233-08-9()Verwandte Suche:


  • CevimelineHClSalt
  • (+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3quinuclidine
  • Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, (2'R,3R)-rel-
  • Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, cis-
  • 2-methyspiro(1,3-oxathiolane-5,3)quinuclidine
  • AF-102B
  • Evoxac
  • SNI-2011
  • Cevimeline
  • (+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine]
  • Hsdb 7286
  • 3]oxathiolane]
  • 3R)-rel-
  • 2-Methyspiro(1,3-oxathiol
  • CeviMeline(Evoxac)
  • AF-102B;FKS-508
  • rac,cis-Cevimeline
  • cis-2-Methyl-1'-azaspiro[[1,3]oxathiolane-5,3'-bicyclo[2.2.2]octane
  • Cevimeline (AF-102B)
  • 107233-08-9
  • C10H18ClNOS
  • C10H17NOSHCl
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Neurochemicals
  • Pharmaceuticals
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