5-Chlorindol
|
|
|
- CAS-Nr.
- 17422-32-1
- Bezeichnung:
- 5-Chlorindol
- Englisch Name:
- 5-Chloroindole
- Synonyma:
- 5-CHLORO-1H-INDOLE;oroindoL;ChloroIndole;5-CHLOROINDOLE;5-CHLOROINDOLE99%;6-Chloroindole99%;5-Chloroindole 98%;5-Chloroindole >5-Chloroindole ,98%;1H-Indole,5-chloro-
- CBNumber:
- CB2126773
- Summenformel:
- C8H6ClN
- Molgewicht:
- 151.59
- MOL-Datei:
- 17422-32-1.mol
|
5-Chlorindol Eigenschaften
- Schmelzpunkt:
- 69-71 °C (lit.)
- Siedepunkt:
- 130 °C / 0.4mmHg
- Dichte
- 1.1976 (rough estimate)
- Brechungsindex
- 1.5437 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- Soluble in alcohol.
- pka
- 16.09±0.30(Predicted)
- Aggregatzustand
- Crystalline Powder
- Farbe
- White to slightly grayish-green
- BRN
- 2651
- InChI
- InChI=1S/C8H6ClN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H
- InChIKey
- MYTGFBZJLDLWQG-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(Cl)C=C2)C=C1
- CAS Datenbank
- 17422-32-1(CAS DataBase Reference)
5-Chlorindol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White to slightly greyish-green crystalline powder
Verwenden
5-Chloroindole is a halo-substituted indole used in the preparation of neurologically active compounds such as atypical antipsychotic agents. 5-Chloroindole has been shown to depress serotonin levels
in the brainstem and telencephalon.
Allgemeine Beschreibung
5-Chloroindole is a 5-substituted indole. It undergoes electropolymerization to form a redox-active film consisting of a cyclic trimer and chains of linked cyclic trimer (polymer). It is a potential positive allosteric modulator (PAM) of the 5-HT
3 receptor. It has been reported as strong inhibitor of the copper dissolution in acidic sodium chloride solution. It has been tested as corrosion inhibitor of mild steel in 1N deaerated sulphuric acid. Synthesis of 5-chloroindole, via nitration of indoline has been described.
l?uterung methode
It is distilled at high vacuum and recrystallises from pet ether (b 40-60o) or (b 80-100o) as glistening plates. The picrate has m 147o (146.5-147.5o)(from *C6H6). [Rydon & Tweddle J Chem Soc 3499 1955, Sugasawa J Org Chem 44 578 1979, Beilstein 20/4 V 34.]
5-Chlorindol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-Chlorindol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 453)Lieferanten
17422-32-1(5-Chlorindol)Verwandte Suche:
- 5-CHLOROINDOLE(5ClI)
- 5-Chloro-1H-indole 98%
- 5-Chloroindole ,98%
- 5-chloro-1H-indole(SALTDATA: FREE)
- 5-CHLOROINDOLE
- 1H-Indole,5-chloro-
- 6-Chloroindole99%
- ChloroIndole
- 5-Chloroindole 98%
- 1H-Indole,5-chloro-(9CI)
- 5-CHLOROINDOLE99%
- 5-chloroindole 17422-32-1
- 5-Chloroindole in stock Factory
- 5-Chloroindole >
- oroindoL
- 5-CHLORO-1H-INDOLE
- 17422-32-1
- 7422-32-1
- Building Blocks
- Simple Indoles
- Indoles
- Heterocyclic Building Blocks
- Halogenated Heterocycles
- Indoles
- INDOLE
- blocks
- IndolesOxindoles
- Indole/indoline/oxindole
- Indole and Indoline
- Indoles and derivatives
- IndoleDerivative
- Halides
- Pyrroles & Indoles
- Building Blocks
- C7 to C10
- C7 to C9
- Chemical Synthesis
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- API Intermediate
- Heterocycle-Indole series
- Simple Indoles
- Pyrroles & Indoles
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- IndolesBuilding Blocks
