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Carprofen

Carprofen Struktur
53716-49-7
CAS-Nr.
53716-49-7
Bezeichnung:
Carprofen
Englisch Name:
Carprofen
Synonyma:
2-(6-chloro-9H-carbazol-2-yl)propanoic acid;rimadyl;rac Carprofen;c5720;imadyl;Ridamyl;Caroline;CARPROFEN;kanujofen;carprofeno
CBNumber:
CB0663159
Summenformel:
C15H12ClNO2
Molgewicht:
273.71
MOL-Datei:
53716-49-7.mol

Carprofen Eigenschaften

Schmelzpunkt:
186-1880C
Siedepunkt:
509.1±35.0 °C(Predicted)
Dichte
1.2011 (rough estimate)
Brechungsindex
1.5200 (estimate)
storage temp. 
Sealed in dry,2-8°C
L?slichkeit
DMSO: soluble20mg/mL, clear
Aggregatzustand
powder
pka
4.84±0.30(Predicted)
Farbe
white to beige
Merck 
14,1862
Major Application
forensics and toxicology
pharmaceutical (small molecule)
InChI
InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)
InChIKey
PUXBGTOOZJQSKH-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(Cl)C=C2)C2=C1C=C(C(C)C(O)=O)C=C2
CAS Datenbank
53716-49-7(CAS DataBase Reference)
EPA chemische Informationen
9H-Carbazole-2-acetic acid, 6-chloro-.alpha.-methyl- (53716-49-7)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T,Xn
R-S?tze: 25-36/37/38-20/21/22
S-S?tze: 45-36-26
RIDADR  UN 2811
WGK Germany  3
RTECS-Nr. FE3180000
HazardClass  6.1
PackingGroup  III
HS Code  29339900
Speicherklasse 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Toxizit?t LD50 orally in mice: 400 mg/kg (Berger, Corraz)
Bildanzeige (GHS) Skull and Crossbones (GHS06)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit

Carprofen Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R25:Giftig beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used in animals to combat pain and inflammation, particularly as associated with osteoarthritis. Like many NSAIDs, carprofen inhibits both cyclooxygenases COX-1 and COX-2 (IC50s = 22.3 and 3.9 μM, respectively). It also inhibits fatty acid amide hydrolase (IC50 = 74 μM), blocking the metabolism of the cannabinoid receptor ligand, arachidonoyl ethanolamide .

Chemische Eigenschaften

Off-White Crystalline Solid

Verwenden

Carprofen is a non steroidal anti-inflammatory that is used by veterinarians for the relief of arthritic systems in dogs. It can be used for joint pain or post operative inflammation. Carprofen, is al so used for the relief from pain and inflammation associated with osteoarthritis, hip dysplasia and other joint issues.

Definition

ChEBI: Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.

Nebenwirkungen

Common side effects of Carprofeng in dogs include vomiting, diarrhoea, loss of appetite, constipation, behavioural changes; and in severe cases, black stools, gastrointestinal ulcers and gastrointestinal haemorrhage, jaundice, skin changes, involuntary muscle movements, and kidney damage (increased thirst, increased urination, and refusal to eat).

Carprofen Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Carprofen Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 449)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Wuhan Fortuna Chemical Co., Ltd
+86-27-59207850
info@fortunachem.com China 5982 58
Zibo Shiji Zhonglian Medical Technology Co., Ltd.
15069388126 15069388126;
sales@sjzlpharm.com China 65 58
Xiamen Wonderful Bio Technology Co., Ltd.
+8613043004613
Sara@xmwonderfulbio.com China 283 58
Anhui Ruihan Technology Co., Ltd
+8617756083858
daisy@anhuiruihan.com China 973 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823
admin@guyunchem.com China 615 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Moxin Chemicals
+86-17320513646 +8617320513646
anna@molcoo.com China 10000 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29640 60
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55

53716-49-7(Carprofen)Verwandte Suche:


  • 6-CHLORO-ALPHA-METHYL-9H-CARBAZOLE-2-ACETIC ACID
  • (+/-)-6-chloro-alpha-methylcarbazole-2-acetic acid
  • CARPROFEN
  • methylcarbazole-2-acetic acid
  • Carprofen,6-Chloro-α-methyl-9H-carbazole-2-acetic acid
  • Carprofen (200 mg)
  • Carprofen (200 mg) (AS)
  • (dl)-6-Chloro-α-Methylcarbazole- 2-acetic Acid
  • 9H-Carbazole-2-acetic acid, 6-chloro-α-methyl-
  • Carprofen Solution, 100ppm
  • Carprofen, >=98%
  • 33975 - VETRANAL, analytical standard
  • Ro-20-5720/000
  • 6-Chloro-a-methyl-9H-carbazole-2-acetic Acid
  • 6-Chloro-α-methylcarbazole-2-acetic acid
  • 9H-Carbazole-2-acetic acid, 6-chloro-.alpha.-methyl-
  • 6-chloro-α-methyl-9h-carbazole-2-acetic acid
  • (+-)-9h-carbazole-2-aceticaci
  • c5720
  • carprofeno
  • dl-6-chloro-alpha-methylcarbazole-2-aceticacid
  • imadyl
  • D-(+)-GLUCOSE SOLUTION (45%) CELL*CULTUR E TESTED
  • Carprofen, 98%, a COX2 inhibitor
  • kanujofen
  • Caroline
  • Carprofen Standard
  • Carprofen CRS
  • Carprofen for system suitability CRS
  • Carprofen >
  • Ridamyl
  • (2RS)-2-(6-Chloro-9H-carbazol-2-yl)propanoic acid
  • 2-(6-chloro-9H-carbazol-2-yl)-3,3,3-trideuteriopropanoic acid
  • Carprofen USP/EP/BP
  • Carprofen-13C,d3
  • CarprofenQ: What is Carprofen Q: What is the CAS Number of Carprofen
  • Carprofen (Y0000846)
  • Carprofen (1096699)
  • chloro-alpha-methylcarbazole
  • 2-(6-Chloro-carbazol-2-yl)-propionic acid
  • Carprofen EP/USP
  • Ridamyl|||Imadyl|||Rimadyl
  • Carprofen in methanol
  • C11045850 Carprofen
  • Pregabalin Impurity 87
  • Carprofen, COX-2 inhibitor
  • Carprofen, 10 mM in DMSO
  • Carprofen 1000 μg/mL in Acetonitrile
  • 6-Chloro-alpha-methyl-9H-carbazol-2-acetic acid
  • (+/-)-6-chloro-alpha-methylcarbazole-2-acetic acid
  • 6-Chloro-α-methyl-9H-carbazole-2-acetic acid
  • rimadyl
  • 2-(6-chloro-9H-carbazol-2-yl)propanoic acid
  • rac Carprofen
  • 53716-49-7
  • 3716-49-7
  • C15H12ClNO2
  • API
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