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(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester

(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester Struktur
1245-00-7
CAS-Nr.
1245-00-7
Englisch Name:
(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester
Synonyma:
Sitsirikine;Methyl (2R)-2-[(2S,12bS)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate;Sitsirikin;16R-sitsirikine;(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester;(16R)-18,19-Didehydro-17-hydroxy-17,18-secoyohimban-16-carboxylic acid methyl ester;Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethenyl-1,2,3,4,6,7,12,12b-octahydro-α-(hydroxymethyl)-, methyl ester, (αR,2S,3R,12bS)-
CBNumber:
CB22320562
Summenformel:
C21H26N2O3
Molgewicht:
354.45
MOL-Datei:
1245-00-7.mol

(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester Eigenschaften

Schmelzpunkt:
239-241℃ (Decomposition)
Siedepunkt:
545.4±50.0 °C(Predicted)
Dichte
1.25±0.1 g/cm3(Predicted)
pka
14.30±0.10(Predicted)

Sicherheit

(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

One of the numerous alkaloids isolated from Vinca species, this base occurs in V. rosea L. and forms colourless crystals from MeOH. It is laevorotatory with[α]26D - 58° (MeOH) and when crystallized from Me2CO forms crystals containing solvent of crystallization, m.p. 181°C. The ultraviolet spectrum in MeOH has absorption maxima at 226, 282 and 290 mf.1. The alkaloid contains a primary alcoholic group and an imino group and yields the hemisulphate, m.p. 239- 241°C (dec.); the picrate, m.p. 226-8°C (dec.) and the O-acetate, m.p. 198°C;[α]26D- 26° (MeOH).

Einzelnachweise

Svoboda et al., J. Pharm. Sci., 50,409 (1961)
Kutney, Brown., Tetrahedron Lett., 1815 (1963)

(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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1245-00-7()Verwandte Suche:


  • (16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester
  • (16R)-18,19-Didehydro-17-hydroxy-17,18-secoyohimban-16-carboxylic acid methyl ester
  • Sitsirikin
  • 16R-sitsirikine
  • Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethenyl-1,2,3,4,6,7,12,12b-octahydro-α-(hydroxymethyl)-, methyl ester, (αR,2S,3R,12bS)-
  • Methyl (2R)-2-[(2S,12bS)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate
  • Sitsirikine
  • 1245-00-7
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