Poziotinib (HM781-36B)

1092364-38-9

CAS-Nr.: 1092364-38-9

Englisch Name:: Poziotinib (HM781-36B)

Synonyma:: Poziotinib;NOV120101;CS-1788;pozytinib;Pozzi for;HM781-36B);UNII-OEI6OOU6IK;Poziotinib(NOV120101;Poziotinib HM-781368;poziotinib(HM-78136B)

CBNumber:: CB22668103

Summenformel:: C23H21Cl2FN4O3

Molgewicht:: 491.34

MOL-Datei:: 1092364-38-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 208

Poziotinib (HM781-36B) Eigenschaften

Schmelzpunkt:: 187 - 190° C

Siedepunkt:: 629.7±55.0 °C(Predicted)

Dichte: 1.409±0.06 g/cm3(Predicted)

storage temp.: -20°C Freezer, Under inert atmosphere

L?slichkeit: Chloroform (Slightly), DMSO (Slightly, Sonicated)

pka: 5.35±0.30(Predicted)

Aggregatzustand: Solid

Farbe: White to Pale Beige

InChIKey: LPFWVDIFUFFKJU-UHFFFAOYSA-N

SMILES: C(N1CCC(OC2C(OC)=CC3C(C=2)=C(NC2=CC=C(Cl)C(Cl)=C2F)N=CN=3)CC1)(=O)C=C

CAS Datenbank: 1092364-38-9

Sicherheit

Poziotinib (HM781-36B) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Poziotinib is a TKI that covalently and irreversibly inhibits EGFR and HER2, and is unique because of its small terminal group and flexible quinazoline core. Its small size and flexibility allow it to evade the steric hindrance which affects other EGFR TKIs [138].

Verwenden

Poziotinib can be used to inhibit the growth of cancer cells.

Poziotinib (HM781-36B) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

6-Quinazolinol, 4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 1-[4-[[(4-Methylphenyl)sulfonyl]oxy]-1-piperidinyl]-2-propen-1-one 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol 4-Piperidinol, 1-(3-chloro-1-oxopropyl)-, 4-(4-methylbenzenesulfonate) 3,4-Dichloro-2-fluoroaniline Acryloylchlorid N,N-Dimethylacetamid Kaliumcarbonat

Downstream Produkte

Poziotinib (HM781-36B) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 208)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
HangZhou RunYan Pharma Technology Co.,LTD.	+8618882027439	sales2@runyanpharma.com	China	302	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
TianYuan Pharmaceutical CO.,LTD	+86-755-23284190 13684996853	sales@tianpharm.com	CHINA	304	58
Shenzhen Excellent Biotech Co., Ltd.	13480692018	ramyan@ex-biotech.com	CHINA	954	58
Jurong Coupling Biotechnology Co., Ltd.	13656108824	coupling278191416@hotmail.com	CHINA	184	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8741	58

1092364-38-9()Verwandte Suche:

5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyron

1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one
UNII-OEI6OOU6IK
1-(4-((4-((3,4-dichloro-2-fluorophenyl)aMino)-7- Methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one
1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one
poziotinib(HM-78136B)
1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one Poziotinib
HM781-36B)
Poziotinib(NOV120101
CS-1788
HM781-36B; NOV120101; NOV-120101; NOV 120101; POZIOTINIB
Poziotinib (HM781-37B)
2-Propen-1-one, 1-[4-[[4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-
Poziotinib HM-781368
pozytinib
Pozzi for
3-Pyridinecarbonitrile,6-fluoro-9-nitro-
Poziotinib (HM-781-36)
Poziotinib, 10 mM in DMSO
NOV120101
Poziotinib
1092364-38-9
C23H21Cl2FN4O3
Inhibitors
API

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