Fluvoxamine maleate
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- CAS-Nr.
- 61718-82-9
- Englisch Name:
- Fluvoxamine maleate
- Synonyma:
- Fluvoxamine for system suitability CRS;Luvox;Fluvoxamine maleate CRS;5-methoxy-4’-trifluoromethylvalerophenone(e)-o-2-aminoethyloximemonomaleate;MK-264;du23000;Dumirox;Faverin;Fevarin;Maveral
- CBNumber:
- CB2722966
- Summenformel:
- C19H25F3N2O6
- Molgewicht:
- 434.41
- MOL-Datei:
- 61718-82-9.mol
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Fluvoxamine maleate Eigenschaften
- Schmelzpunkt:
- 120-121.5 °C
- Flammpunkt:
- 9℃
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: soluble
- Aggregatzustand
- solid
- Farbe
- White to Off-White
- Wasserl?slichkeit
- Soluble in water (10mM)
- Merck
- 14,4219
- BCS Class
- 1
- InChI
- 1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-
- InChIKey
- LFMYNZPAVPMEGP-PIDGMYBPSA-N
- SMILES
- C(C1C=CC(=CC=1)/C(=N\OCCN)/CCCCOC)(F)(F)F.C(O)(=O)/C=C\C(O)=O
- CAS Datenbank
- 61718-82-9(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn,Xi |
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| R-S?tze: |
22-36/37/38 |
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| S-S?tze: |
36-36/37/39-27-26 |
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| RIDADR |
UN1230 - class 3 - PG 2 - Methanol, solution |
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| WGK Germany |
3 |
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| RTECS-Nr. |
SA9230000 |
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| HS Code |
29280000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Fluvoxamine maleate Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getr?nkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Fluvoxamine maleate is the most recent of the serotonin-specific antidepressants
to reach the market. In vitro and in vivo animal experiments have shown
fluvoxamine to have a marked effect on 5-HT mediated processes and little effect
on norepinephrine. Clinical trials suggest similar efficacy to imipramine and
clomipramine with a somewhat lower incidence of side effects, especially anticholinergic
effects. Fluvoxamine, in contrast to the tricyclic antidepressants,
does not appear to produce heart rate increase, postural hypotension or prolongation
of the intraventricular conduction time and QT interval.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Fluvoxamine maleate has been used as a test compound to determine the solubility and effective blood-brain barrier permeability.(2)
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Hazard
A poison by ingestion. Human systemic
effects.
Biologische Aktivit?t
Selective serotonin reuptake inhibitor; antidepressant. Binds to the human 5-HT transporter with a K i of 1.6 nmol/l. Also available as part of the Serotonin Uptake Inhibitor Tocriset™ .
Fluvoxamine maleate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Fluvoxamine maleate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 478)Lieferanten
61718-82-9()Verwandte Suche:
- FLUVOXAMINE MALEATE
- (E)-5-METHOXY-1-[4-(TRIFLUOROMETHYL)PHENYL]-1-PENTANONE-O-(2-AMINOETHYL)OXIME MALEATE
- 1-pentanone,5-methoxy-1-(4-(trifluoromethyl)phenyl)-,o-(2-aminoethyl)oxime,(
- du23000
- faverin50
- (E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]-O-(2-aminoethyl)oxime-1-pentanone
- Fluvoxamine maleate,(E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
- Fluvoxamine Maleate (200 mg)
- (E)-5-Methoxy-1-(4-(trifluoroMethyl)phenyl)pentan-1-one O-(2-aMinoethyl) oxiMe Maleate
- (E)-5-Methoxy-1-[4-(trifluoroMethyl)]-1-pentanone-O-(2-aMinoehyl)oxiMe Maleate
- 2-[[5-Methoxy-1-[4-(trifluoromethyl)phenyl]-pentylidene]amino]oxyethanamine maleate
- MK-264, DI-23000, Dumirox, Flaverrin, Fevarin, Floxyfral, Luvox, Maveral, (E)-5-Methoxy-1-[4-(triflurormethyl)phenyl]-1-pentanone, Maleate,
- (E)-5-Methoxy-1-(4-(trifluoromethyl)phenyl)pentan-1-one O-2-aminoethyl oxime
- 1-Pentanone, 5-methoxy-1-4-(trifluoromethyl)phenyl-, O-(2-aminoethyl)oxime, (1E)-, (2Z)-2-butenedioate (1:1)
- Fluvoxamine Maleat
- (E)-5-Methoxy-1-[4-(triflurormethyl)phenyl]-1-pentanone O-(2-Aminoethyl)oxime Maleate
- Dumirox
- Faverin
- Fevarin
- Floxyfral
- Maveral
- MK-264
- (E)-Fluvoxamine Maleate
- FluvoxaMine Meleate
- 1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl)phenyl]-, O-(2-aminoethyl)oxime, (1E)-, (2Z)-2-butenedioate
- Fluvoxamine maleate, 98%, a selective serotonin (5-HT) reuptake inhibitor (SSRI)
- FluvoxamineMaleate>
- Fluvoxamine Maleate RS
- DU-23000 (maleate)
- Fluvoxamine maleate USP/EP/BP
- Fluvoxamine maleate (DU23000 maleate)
- Fluvoxamine D4 MaleateQ: What is
Fluvoxamine D4 Maleate Q: What is the CAS Number of
Fluvoxamine D4 Maleate Q: What is the storage condition of
Fluvoxamine D4 Maleate Q: What are the applications of
Fluvoxamine D4 Maleate
- Fluvoxamine maleateQ: What is
Fluvoxamine maleate Q: What is the CAS Number of
Fluvoxamine maleate Q: What is the storage condition of
Fluvoxamine maleate Q: What are the applications of
Fluvoxamine maleate
- "Fluvoxamine Maleate 13C, D3"
- Fluvoxamine Maleate (1285909)
- Fluvoxamine for system suitability CRS
- FLUVOXAMINE MALEATE IP/BP/USP
- Fluvoxamine (DU-23000) maleate
- Fluvoxamine maleate in methanol
- Fluvoxamine maleate, Serotonin reuptake inhibitor (SSRI)
- Fluvoxamine maleate, 10 mM in DMSO
- FLUVOXAMINE MALEATE USP
- Fluvoxamine maleate - Bio-X ?
- Fluvoxamine.maleate, 1mg/ml in Methanol (as free base)
- D4-Fluvoxamine Maleate
- (E)-5-Methoxy-1-(4-(trifluoromethyl)phenyl)-O-(2-aminoacetamido)-1-pentanone maleate
- (E)-(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine
- Fluvoxamine maleate (Standard)
- 5-methoxy-4’-trifluoromethylvalerophenone(e)-o-2-aminoethyloximemonomaleate
- Fluvoxamine maleate CRS
- Luvox
- 61718-82-9
- 61718-82-8
- 61717-82-9
- C15H21F3N2O2C4H4O
- C19H25F3N2O6
- C14H18F3N2O2C4H4O4
- ESTROVIS
