N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide
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- CAS-Nr.
- 76820-34-3
- Englisch Name:
- N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide
- Synonyma:
- 5-Nitro-N,N'-bis(2,3-dihydroxypropyl)isophthalamide;Iohexol USP RC C;Iohexol Impurity 16;Iohexol Related CoMpound C;Iohexol USP Related Compound C;N,N'-Bis(2,3-dihydroxypropyl)-5-nit;Iohexol Impurity 18（Iohexol USP RC C）;N,N'-Bis(2,3-Dihydorxypropyl)-5-Benzenediformamide;N,N-Bis-(2,3-dihydroxypropyl)-5-nitroisophthalamide;N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-m-phthalamide
- CBNumber:
- CB3258398
- Summenformel:
- C14H19N3O8
- Molgewicht:
- 357.32
- MOL-Datei:
- 76820-34-3.mol
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N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Eigenschaften
- Schmelzpunkt:
- >140°C (dec.)
- Dichte
- 1.347 at 20℃
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilit?t:
- Hygroscopic
- Major Application
- pharmaceutical (small molecule)
- InChI
- InChI=1S/C14H19N3O8/c18-6-11(20)4-15-13(22)8-1-9(3-10(2-8)17(24)25)14(23)16-5-12(21)7-19/h1-3,11-12,18-21H,4-7H2,(H,15,22)(H,16,23)
- InChIKey
- LJEBHEAPZMNBSI-UHFFFAOYSA-N
- SMILES
- C1(C(NCC(O)CO)=O)=CC([N+]([O-])=O)=CC(C(NCC(O)CO)=O)=C1
- LogP
- -1.36 at 23℃ and pH6
- CAS Datenbank
- 76820-34-3(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| HS Code |
2924296000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P332+P313 |
Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P337+P313 |
Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is a non-ionic organic compound that can be used as a reaction intermediate for the preparation of amidated iodinated x-ray contrast media. The amidation reaction is typically carried out in aqueous solution with an acid catalyst at room temperature for up to 24 hours. The amidation reaction condition and time can be optimized depending on the desired end product. Industrial preparation of iohexol typically involves the use of an x-ray generator and iopamidol, which is synthesized from diethylene triamine and ethylenediamine.
Chemische Eigenschaften
White to Off-White Solid.
Verwenden
N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is used in the preparation of X-ray contrast agents.
N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 109)Lieferanten
76820-34-3()Verwandte Suche:
- N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-5-NITRO-1,3-BENZENEDICARBOXAMIDE
- N,N`-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenediformamide
- N,N-Bis-(2,3-dihydroxypropyl)-5-nitroisophthalamide
- 5-AMINO C N,N'' C BIS (2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-1,3-BENZENEDICARBOXAMIDE
- N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide
- 5-Nitro-N,NBis(2,3-Dihydroxypropyl)-1,3-Benzenedicarbolamide
- Iohexol Related Compound C (50 mg) (N,N'-bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide)
- 5-NITRO-N,N'-BIS(2,3-DIHYDROXYPROPYL)-1,3-BENZENEDICARBOXAMIDE[IOHEXOL INTERMEDIATE]
- N,N'-Bis(2,3-Dihydorxypropyl)-5-Benzenediformamide
- 1-N,3-N-bis(2,3-dihydroxypropyl)-5-nitrobenzene-1,3-dicarboxaMide
- N1,N3-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxaMide
- N1,N3-Bis(2,3-dihydroxypropyl)-5-nitroisophthalamide
- Iohexol Related CoMpound C
- Iohexol USP Related Compound C
- Iohexol Impurity Ⅲ:N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide
- Iohexol Impurity 18（Iohexol USP RC C）
- N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-nitrobenzene-1,3-dicarboxamide
- N,N'-Bis(2,3-dihydroxypropyl)-5-nit
- N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxam
- Iohexol USP RC C
- 1,3-Benzenedicarboxamide, N1,N3-bis(2,3-dihydroxypropyl)-5-nitro-
- N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-m-phthalamide
- N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxami...
- Iohexol Related compound CQ: What is
Iohexol Related compound C Q: What is the CAS Number of
Iohexol Related compound C Q: What is the storage condition of
Iohexol Related compound C Q: What are the applications of
Iohexol Related compound C
- Iohexol Impurity 16
- N,N'-bis(2,3-dihydroxypropyl)-5-nitrobenzene-1,3 dicarboxamide
- 5-Nitro-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
- 5-Nitro-N,N'-Bis(2,3-DihydroxyPropyl)-1,3-BenzenedimethylAmide
- 76820-34-3
- C14H16I3N3O8
- Aromatics
- Intermediates
- Labeling and Diagnostics Reagents
