Phosphokreatin
|
|
|
- CAS-Nr.
- 67-07-2
- Bezeichnung:
- Phosphokreatin
- Englisch Name:
- Creatine phosphate
- Synonyma:
- phosphocreatine;2-(1-Methyl-3-phosphonoguanidino)acetic acid;Glycine, N-[imino(phosphonoamino)methyl]-N-methyl-;Neoton;phosphagen;n-phosphocreatine;CREATINE PHOSPHATE;N-Phosphorocreatine;Creatine phosphoric acid;Creatine phosphate USP/EP/BP
- CBNumber:
- CB3266807
- Summenformel:
- C4H10N3O5P
- Molgewicht:
- 211.11
- MOL-Datei:
- 67-07-2.mol
|
Phosphokreatin Eigenschaften
- Schmelzpunkt:
- >175oC (dec.)
- Siedepunkt:
- 449.1±47.0 °C(Predicted)
- Dichte
- 1.83±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- L?slichkeit
- Water
- pka
- pKa 4.7± 0.01(H2O,t =25)(Approximate)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilit?t:
- Hygroscopic
- InChI
- InChI=1S/C4H10N3O5P/c1-7(2-3(8)9)4(5)6-13(10,11)12/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12)
- InChIKey
- DRBBFCLWYRJSJZ-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CN(C(=N)NP(O)(O)=O)C
- CAS Datenbank
- 67-07-2(CAS DataBase Reference)
- EPA chemische Informationen
- Glycine, N-[imino(phosphonoamino)methyl]-N-methyl- (67-07-2)
Phosphokreatin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Phosphocreatine used in the synthesis of hydroxypatite nanorod/nanosheets. Phosphocreatine is used in the treatment of heart and brain ischemia.
Enzyminhibitor
This phosphagen (FW = 211.11 g/mol; CAS 67-07-2; 922-32-7 for disodium salt), known almost as commonly as creatine phosphate, is the primary cytosolic phosphoryl donor for the resynthesis of MgATP from MgADP through the action of creatine kinase in vertebrates and some invertebrates. While abundant in skeletal and cardiac muscle (40-60 mM), nonmuscle cells contain 3-5 mM, and some fungi (e.g., Candida) have intermediate levels of this metabolite. Note: The reported inhibitory action by creatine kinase is often due to impurities (e.g., the inhibition of 5’- nucleotidase is due to an impurity in the commercial phosphocreatine). The reported inhibition of AMP deaminase is due mainly to the presence of pyrophosphate. Phosphocreatine is a hygroscopic solid and very soluble in water. Unstable in acid, all is hydrolyzed after one minute at 100°C in 1.0 M HCl, and half is hydrolyzed in 4 min at 25°C in 0.5 M HCl. Molybdate and certain buffers reportedly accelerate hydrolysis. Hydrolysis is slow under slightly alkaline conditions (e.g., pH 7.8). Nevertheless, solutions should always be freshly prepared and stored frozen. Target(s): adenylate cyclase; AMP deaminase; glutamine synthetase; H+-extrusion by plasma membrane ATPase; NADH peroxidase; phosphofructokinase; and thiamin-phosphate diphosphorylase.
Phosphokreatin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Phosphokreatin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 148)Lieferanten
67-07-2(Phosphokreatin)Verwandte Suche:
- n-phosphocreatine
- n-(phosphonoamidino)-sarcosine
- CREATINE PHOSPHATE
- n-[imino(phosphonoamino)methyl]-n-methyl-glycin
- N-(N1-(dihydroxyphosphinyl)amidino)sarcosine
- PhosphoCreatineSodiumC4H8N3Na2O5P
- Creatine phosphoric acid
- 2-[methyl-(N'-phosphonocarbamimidoyl)amino]acetic acid
- Neoton
- N-Phosphorocreatine
- phosphagen
- Creatine Phosphate (Phosphocreatine), >
- Creatine Phosphate (Phosphocreatine)
- Creatine phosphate USP/EP/BP
- Creatine Phosphate (Phosphocreatine), >85%
- 2-(1-Methyl-3-phosphonoguanidino)acetic acid
- Glycine, N-[imino(phosphonoamino)methyl]-N-methyl-
- Creatine phosphate monosodium salt hexahydrate
- phosphocreatine
- 67-07-2
- 67-7-2
- 967-07-2
- 1967-07-2
- H2PO3NHCNHNCH3CH2COOH
- C4H10N3O5P
- C4H8N3O5PNa2
- HO2OPNHCNHNCH3CH2COOH
