(S)-3-[3-(tert-Butylamino)-2-hydroxypropoxy]-4-morpholino-1,2,5-thiadiazolmonomaleat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R63:Kann das Kind im Mutterleib m?glicherweise sch?digen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Timolol is a non-selective β-adrenergic receptor antagonist with log K_d values of -8.27, -9.86, and -6.8 for binding to human β₁-, β₂-, and β₃-adrenoceptors, respectively. It has been reported that only the (S) enantiomer contributes to the β-blocking effects of racemic timolol, but the weakly active (R) isomer maintains a beneficial effect on intraocular pressure without the undesirable side-effect of bronchial constriction caused by non-selective action of (S)-timolol on β₁ and β₂ receptors. Timolol has been use alone and in fixed combinations with either prostaglandin analogs or carbonic anhydrase inhibitors to reduce intraocular pressure in research models of ocular hypertension and glaucoma.

Chemische Eigenschaften

White Solid

Verwenden

betaadrenergic blocker

Definition

ChEBI: The maleic acid salt of the active (S)-enantiomer of timolol, comprising equimolar amounts of (S)-timolol and maleic acid.

Biologische Aktivit?t

β 1 -adrenergic blocker.

(S)-3-[3-(tert-Butylamino)-2-hydroxypropoxy]-4-morpholino-1,2,5-thiadiazolmonomaleat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(S)-3-[3-(tert-Butylamino)-2-hydroxypropoxy]-4-morpholino-1,2,5-thiadiazolmonomaleat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shandong Xuhuang New material CoLTD	+86-15095020839 +86-17660422208		China	726	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Jinan Jianfeng Chemical Co., Ltd	+86-0531-88110457 +8615562555968	info@pharmachemm.com	China	310	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
Hebei shuoxi biotechnology co. LTD	+8613081092107		CHINA	964	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58

26921-17-5((S)-3-[3-(tert-Butylamino)-2-hydroxypropoxy]-4-morpholino-1,2,5-thiadiazolmonomaleat)Verwandte Suche:

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• S[-]-1-[T-BUTYLAMINO]-3-(4-MORPHOLINO-1,2,5-THIADIAZOL-3-YL)OXY]-2-PROPANOL MALEATE SALT
• (S)-1-[(1,1-DIMETHYLETHYL)AMINO]-3-[[4-(4-MORPHOLINYL)-1,2,5-THIADIAZOL-3-YL]OXY]-2-PROPANOL MALEATE
• (s)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol (z)-2-butenedioate (1:1)
• (-)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-2-propan
• (s)-timololhydrogenmaleate
• 1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-2-propano(
• betime
• l-timololmaleate
• mk950
• olmaleate
• timacor
• 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1) (salt) (9CI)
• 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (S)-, (Z)-2-butenedioate (1:1) (salt)
• Aquanil
• Betim
• Blocanol
• Optimol
• Proflax
• Rysmon TG
• Temserin
• Tenopt
• Timacar
• Timoptol
• Timoptol XE
• Timorom
• WP 934
• (S)-3-[3-(tert.-Butylamino)-2-hydroxypropoxy]-4-morpholino-1,2,5-thiadiazolmonomaleat
• 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1)
• Timolol maleate, >=99%
• Timclol Maleate
• (2S)-1-(tert-Butylamino)-3-(4-morpholino-1,2,5-thiadiazole-3-yloxy)-2-propanol·maleic acid
• Thiaboot
• Timabak
• Timolol hydrgenmaleate
• Timolol Maleate (200 mg)
• ToMolol Maleate
• (2S)-1-[(1,1-DiMethylethyl)aMino]-3-[[4-(4-Morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-
• (S)-1-(tert-butylaMino)-3-((4-Morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol Maleate
• Hydrogen maleate salt
• Timolol for system suitability
• TIMOLOL HYDROGENMALEATE
• (S)-TIMOLOL MALEATE
• (s)-3-[3-(tert-butylamino)-2-hydroxypropoxy]-4-morpholino-1,2,5-thiadiazole monomaleate
• S-(-)-1-[T-BUTYLAMINO]-3-[(4-MORPHOLINO-1,2,5-THIADIAZOL-3-YL)OXY]-2-PROPANOL MALEATE SALT
• tert-butyl-[(2S)-2-hydroxy-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]propyl]ammonium
• Timolol for system suitability CRS
• L-714,465 (Maleate)
• (S)-Timolol maleate USP/EP/BP
• Timolol Maleate (L-714,465 Maleate
• Timolol maleateQ: What is Timolol maleate Q: What is the CAS Number of Timolol maleate Q: What is the storage condition of Timolol maleate Q: What are the applications of Timolol maleate
• Timolol for system suitability (Y0001270)Q: What is Timolol for system suitability (Y0001270) Q: What is the CAS Number of Timolol for system suitability (Y0001270)
• Timolol Maleate (1667406)
• timoptic
• 2-Propanol, 1-(1,1-dimethylethyl)amino-3-4-(4-morpholinyl)-1,2,5-thiadiazol-3-yloxy-, (2S)-, (2Z)-2-butenedioate (1:1) (salt)
• Timolol maleate CRS
• (S)-Timolol maleat
• Timolol maleate in methanol
• (S)-Timolol maleate, non-selective beta adrenoceptor antagonist