3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
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- CAS-Nr.
- 130049-82-0
- Englisch Name:
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- Synonyma:
- 3-(2-CHLOROETHYL)-9-HYDROXY-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE;Paliperidone Int 1;3-(2-chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one;3-(2-ChL;Paliperidone-8;Paliperidone USP RC C;3-(2-Chloroethyl)-6,7;Paliperidone IMpurity N;Paliperidone Impurity 55;Paliperidone Impurities105
- CBNumber:
- CB41175684
- Summenformel:
- C11H15ClN2O2
- Molgewicht:
- 242.7
- MOL-Datei:
- 130049-82-0.mol
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3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Eigenschaften
- Schmelzpunkt:
- 100-102°C
- Siedepunkt:
- 389.3±52.0 °C(Predicted)
- Dichte
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 12.97±0.60(Predicted)
- Farbe
- Pale Orange to Yellow
- Major Application
- pharmaceutical (small molecule)
- InChI
- InChI=1S/C11H15ClN2O2/c1-7-8(4-5-12)11(16)14-6-2-3-9(15)10(14)13-7/h9,15H,2-6H2,1H3
- InChIKey
- JKVUGXRJSYRXFN-UHFFFAOYSA-N
- SMILES
- C12C(O)CCCN1C(=O)C(CCCl)=C(C)N=2
- CAS Datenbank
- 130049-82-0(CAS DataBase Reference)
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Pale-Yellow Solid
Einzelnachweise
[1] Pavankumar V. Solanki . “Preparation of 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, a Key Intermediate for the Synthesis of Paliperidone.” Organic Preparations and Procedures International 48 3 (2016): Pages 296-302.
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Upstream-Materialien And Downstream Produkte
Upstream-Materialien
4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-9-(phenylmethoxy)-
3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)
9-Benxyloxy-3-(2-Chloro ethyl)-2-methyl pyrido[1,2-a]pyrimidine-4-one
3-Ethyl-6,7,8,9-tetrahydro-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
Paliperidone Impurity 12
4H-Pyrido[1,2-a]pyrimidine-4,9(6H)-dione, 3-(2-chloroethyl)-7,8-dihydro-2-methyl-, 9-oxime
3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride
3-Benzyloxy-2-pyridylamin
2-Amino-3-hydroxypyridine
α-Acetyl-γ-butyrolacton
Downstream Produkte
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 336)Lieferanten
130049-82-0()Verwandte Suche:
- 3-(2-Chloroethyl)-2-methyl-9-hydroxy-6,7,8,9-tetrahydro-4H-pyrido [1,2-a] pyrimidin-4-one
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-α]pyrimidin-4-one
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidine-4-one
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one ,98%
- Paliperidone Intermediate 1
- 9-tetrahydro-9-hydroxy-2-Methyl-
- 9-Hydroxy-3-(2-chloroethyl)-2-Methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyriMidin-4-one
- 3-(2-chloroethyl)-9-hydroxy-2-Methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyriMidin-4-one
- 4H-Pyrido[1,2-a]pyriMidin-4-one,3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-Methyl-
- 3-(2-CHLOROEETHYL)-6,7,8,9-TETRAHYDRO-9-HYDROXY-2-METHYL-4H-PYRIDO (1,2-A) PYRIMIDIN-4-ONE
- Paliperidone Chloro IMpurity (USP RelatedCoMpound C)
- Paliperidone USP RC C
- Paliperidone IMpurity N
- Paliperidone Related CoMpound C
- Paliperidone Related Compound C (20 mg) (3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-alpha]pyrimidin-4-one)
- -(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- 3-(2-Chloroethyl)-9-hydroxy-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- Paliperidone Related Compound C (3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-alpha]pyrimidin-4-one)
- 3-(2-Chloroethyl)-6,7
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-p
- Paliperidone Impurity 9(Paliperidone USP RC C)
- Paliperidone USP Related Compound C
- Paliperidone-8
- 3-(2-chloroethyl)-9-hydroxy-2-methyl-
- )-6,7,8,9-tetrahydro-9-hydroxy-2-methyL
- 3-(2-ChL
- -4H-pyrido[1,2-a]pyrimidine-4-one
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrimidin-4-one
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one ISO 9001：2015 REACH
- Paliperidone Related Compound C (Paliperidone Chloroethyl Impurity)
- Paliperidone Impurities105
- "3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido-[1,2-a] pyrimidine-4-one"
- 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 130049-82-0
- Paliperidone Related Compound C (3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[ (1491831)
- Paliperidone Impurity 55
- 3-(2-Chloroethy)-6,7,8,9- Tetrahydro-2-methyl-4H- pyrido-(1,2-a) pyrimidine-4- one, Hydrochloride
- 3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-on
- 3-(2-Chloro)-2-methyl-9-hydroxy-6,7,8,9-tetrahydro-4H-piperido[1,2-a]pyrimidin-4-one
- 3-(2-CHLORETHYL)-9-HYDROXY-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1，2-A]PYRIMIDIN-4-ONE
- 3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyridinebenzo[1,2-a]pyrimidine-4-one
- Paliperidone Impurity: (3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-alpha]pyrimidin-4-one)
- Paliperidone Impurity 9（Paliperidone USP Related Compound C）
- 3-(2-chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
- 3-(2-CHLOROETHYL)-9-HYDROXY-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
- Paliperidone Int 1
- 130049-82-0
- C11H15O2N2Cl
- Heterocyclic Compounds
- Bases & Related Reagents
- Heterocycles
- Nucleotides
