Paliperidone Palmitate
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- CAS-Nr.
- 199739-10-1
- Englisch Name:
- Paliperidone Palmitate
- Synonyma:
- Invega Sustenna;Paliperidone Palmitate [USAN];RO 92670;Paliperidone Palmitate;Paliperidone Palmitate-d31;Palmitic acid paliperidone;9-Hydroxyrisperidone palmitate;Palmitone Palmitate Impurity 4;Palmitone Palmitate Impurity 6;Palmitone Palmitate Impurity 3
- CBNumber:
- CB82519012
- Summenformel:
- C39H57FN4O4
- Molgewicht:
- 664.89
- MOL-Datei:
- 199739-10-1.mol
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Paliperidone Palmitate Eigenschaften
- Schmelzpunkt:
- 110-115°C
- Siedepunkt:
- 736.3±70.0 °C(Predicted)
- Dichte
- 1.19
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- L?slichkeit
- Chloroform (Slightly), Ethyl Acetate (Slightly, Heated, Sonicated), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 8.07±0.10(Predicted)
- Farbe
- Off-White to Light Beige
- InChIKey
- VOMKSBFLAZZBOW-UHFFFAOYSA-N
- SMILES
- C(OC1C2N(CCC1)C(=O)C(CCN1CCC(C3C4=C(ON=3)C=C(F)C=C4)CC1)=C(C)N=2)(=O)CCCCCCCCCCCCCCC
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications |
Acute Tox. 3 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P321 |
Besondere Behandlung |
| P330 |
Mund ausspülen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Paliperidone Palmitate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Paliperidone palmitate is an atypical long acting antipsychotics，which
can fast onset in acute phase and continuously improve the symptoms in
maintenance phase． It has the solid efficacy and convenient
ad[1]ministration，which offer a new option for schizophrenia treatment
and will help patients to adhere the treatment and prevent relapse． As
the sole long acting antipsychotics with monthly injection，it was
approved by CFDA in 2011 and indicated for the acute and maintenance
treatment of schizophrenia．
Verwenden
Paliperidone Palmitate is a long-acting injectable atypical antipsychotic used in the treatment of schizophrenia.
Nebenwirkungen
The review of the literature also underlined that paliperidone palmitate
is well tolerated, compared with placebo. Frequency and severity of
side-effects such as extrapyramidal symptoms, hyperprolactinemia and
weight gain, was similar or less than those found in treatment with
other atypical antipsychotics, including long-acting ones.
Paliperidone Palmitate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Paliperidone Palmitate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 246)Lieferanten
199739-10-1()Verwandte Suche:
- (9RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)et
hyl)-2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyriMi
din-9-yl hexadecanoate
- Hexadecanoic acid 3-[2-[4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]-ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester
- Paliperidone Palmitate
- RO 92670
- 9-Hydroxyrisperidone palmitate
- Hexadecanoic acid 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester
- Paliperidone Palmitate-d31
- Paliperidone Impurity 39 (Paliperidone Palmitate)
- 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl palmitate
- Paliperidone Palmitate USP/EP/BP
- Paliperidone palmitateQ: What is
Paliperidone palmitate Q: What is the CAS Number of
Paliperidone palmitate Q: What is the storage condition of
Paliperidone palmitate Q: What are the applications of
Paliperidone palmitate
- Invega Sustenna
- Palmitic acid paliperidone standard
- Paliperidone Palmitate Benzisoxazole Impurity
- Palmitone Palmitate Impurity 4
- Palmitone Palmitate Impurity 6
- Palmitone Palmitate Impurity 3
- Palmitone Palmitate Impurity 2
- Palmitic acid paliperidone impurity 3
- Palmitic acid paliperidone impurity 1
- Palmitic acid paliperidone impurity 5
- Palmitic acid paliperidone impurity 2
- Palmitone Palmitate Impurity 5
- Palmitic acid paliperidone impurity 4
- Palmitic acid paliperidone impurity
- Paliperidone Impurity: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl Ester
- Paliperidone Palmitate [USAN]
- Palmitic acid paliperidone impurities
- Palmitic acid paliperidone
- 199739-10-1
- C39H57FN4O4
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- API
