Oligomycin A
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- CAS-Nr.
- 579-13-5
- Bezeichnung:
- Oligomycin A
- Englisch Name:
- OLIGOMYCIN A
- Synonyma:
- OLIGOMYCIN COMPLEX;CS-1898;Oli;MCH 32;mycin A;AOligoMyci;OLIGOMYCIN A;Oligomycin A, >=98%;Oligomycin A
MCH 32;OLIGOMYCIN A USP/EP/BP
- CBNumber:
- CB4274065
- Summenformel:
- C45H74O11
- Molgewicht:
- 791.06
- MOL-Datei:
- 579-13-5.mol
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Oligomycin A Eigenschaften
- Schmelzpunkt:
- 150-151℃
- Siedepunkt:
- 886.3±65.0 °C(Predicted)
- Dichte
- 1.14
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- L?slichkeit
- Soluble in DMSO, ethanol or acetone
- pka
- 12.52±0.70(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to off-white
- Merck
- 13,6902
- BRN
- 5702132
- InChIKey
- MNULEGDCPYONBU-WMBHJXFZSA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn,T |
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| R-S?tze: |
22-68/20/21/22-20/21/22 |
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| S-S?tze: |
36/37-24/25 |
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| RIDADR |
2811 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
RK3325000 |
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| F |
3-10 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| HS Code |
29419090 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P330 |
Mund ausspülen. |
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Oligomycin A Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R68/20/21/22:Gesundheitssch?dlich: M?glichkeit irreversiblen Schadens durch Einatmen,Berührung mit der Haut und durch Verschlucken.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Beschreibung
Oligomycins are macrolides created by
Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F
1F
O ATP synthase that induces apoptosis in a variety of cell types (average GI
50 = 270 nM). Oligomycin A exhibits antifungal, antitumor, and nematocidal activities, but has poor solubility in water and other biocompatible solvents, which limits its clinical application.
Chemische Eigenschaften
White powder
Verwenden
Oligomycin A is a macrolide with fungicidal activity isolated from Streptomyces species.
Oligomycin A Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Oligomycin A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 225)Lieferanten
579-13-5(Oligomycin A)Verwandte Suche:
- OLIGOMYCIN A, STREPTOMYCES DIASTATOCHROMOGENES
- OLIGOMYCIN A
- OLIGOMYCIN, STREPTOMYCES DIASTATOCHROMOGENES
- Oligomycin A fromStreptomyces diastatochromogenes
- (1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione
- (1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonaMethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonaco
- MCH 32
- AOligoMyci
- mycin A
- Oli
- Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-,(1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16
- Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-
- Oligomycin A
MCH 32
- Oligomycin A, >=98%
- Oligomycin A, 99%, from Streptomyces diastatochromogenes
- Oligomycin A from Streptomyces
- OLIGOMYCIN A USP/EP/BP
- (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-((R)-2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-2,26-dioxaspiro[bicyclo[23.3.1]nonacosa[4,18,20]triene-27,2'-pyran]-3,9,13-trione
- (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-((R)-2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-2,26-dioxaspiro[bicyclo[23.3.1]nonacosa[4,18,20]triene-27,2'-
- OLIGOMYCIN COMPLEX
- CS-1898
- Oligomycin A, ATP synthase inhibitor
- Oligomycin A, 10 mM in DMSO
- 579-13-5
- Antibiotics
- Antibiotics N-S
- Antibiotics A to Z
- BioChemical
- Inhibitors
- antibiotic
- Antibiotics
- AntifungalAntibiotics
- Antineoplastic and Immunosuppressive AntibioticsAntibiotics
- Inhibits an EnzymeAntibiotics
- Antibiotics A to
- Antibiotics by Application
- Antibiotics N-SAntibiotics
- Chemical Structure Class
- Macrolides
- Mechanism of Action
- Spectrum of Activity
- API
